نتایج جستجو برای: hydrazides

تعداد نتایج: 849  

2010
Maria Anna Köllner Detlef Geffken

The anthranilic scaffold plays an important role as a pharmacophore and toxophore in medicinal and agricultural chemistry and contributes to a variety of biological activities [1 – 9]. Although ring-closure reactions of N-unsubstituted anthranilic acid derivates have been extensively elaborated, investigations towards the corresponding chemistry of N-alkyl(aryl)-anthranilic acids remained fragm...

2011
KI Bhat K Sufeera Sunil Kumar P Chaitanya

The reaction of p-bromoanilino acetohydrazide(II) with aromatic aldehydes in alcohol yielded 2-[4-bromo aniline] N-substituted benzylidine hydrazides (IIIa-IIIj), which in presence of yellow mercuric oxide and iodine in DMF, yielded corresponding 4-bromo[(N-5-substituted 1,3,4 oxadiazole-2 -yl)methyl]aniline (IVa-IVj). Structures of the compounds synthesized were confirmed by IR, (1)HNMR and MA...

2012
Vinod Kumar Pandey Zehra Tusi Sumerah Tusi Madhawanand Joshi

A series of novel 4-amino-5-mercapto-3-[(3-aralkyl amido/imidoalkyl) phenyl]-1,2,4-triazoles (5a-d) were obtained by treating m-(aralkyl amido/imidoalkyl) benzoic acid hydrazides (3a-d) with carbon disulphide in alcoholic KOH and hydrazine hydrate, respectively. These triazole derivatives were employed in the synthesis of 5-[(3'-aralkyl amido/imidoalkyl) phenyl]-1,2,4-triazolo[3,4-b]-1,3,4-thia...

Journal: :Acta poloniae pharmaceutica 2015
Amara Mumtaz Aamer Saeed Aneela Maalik Wajiha Khan Saira Azhar Nighat Fatima Asma Zaidi Muhammad Atif

Pyrazolines are biologically and pharmaceutically very active scaffolds. Derivatives of. (3,5-diphenyl-4,5-dihydro-1H-pyrazol-1-yl)(phenyl)methanone were synthesized by the cyclization of chalcones (1a-c) with substituted benzyl hydrazides (2a-e) using a few drops of piperidine as catalyst. Structures of all the synthesized compounds were confirmed by FTIR, 1H NMR, 13C NMR and mass spectrometri...

Journal: :The Analyst 2014
Juan Zhang Junhui Cui Ying Liu Yangyang Chen Genxi Li

In this paper, we report a novel electrochemical method that can be developed as a biosensor for simple and direct determination of α-amylase activity. The method is based on the hydrolysis of maltopentaose, the substrate of the enzyme, which is immobilized on the surface of a gold electrode, and the induced charge changes of the substrate-modified electrode. Specifically, the substrate maltope...

2008
Hoong-Kun Fun Samuel Robinson Jebas K. V. Sujith B. Kalluraya

In the title compound, C(21)H(26)N(2)O, the dihedral angle between the two aromatic rings is 85.90 (19)°. The propenone-hydrazide unit forms dihedral angles of 21.62 (8) and 72.83 (9)°, respectively, with the terminal and central aromatic rings. The 2-methyl-propyl group is disordered over two sites, with occupancies of 0.533 (13) and 0.467 (13). In crystal structure, mol-ecules are linked into...

Journal: :Journal of the Turkish Chemical Society, Section A: Chemistry 2018

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