Due to its high density and close-to-SRAM read latency, spin transfer torque RAM (STT-RAM) is considered one of the most-promising emerging memory technologies for designing large last level caches (LLCs). However, in deep sub-micron region, STT-RAM shows read-disturbance error (RDE) whereby a read operation may modify the stored data value and this presents a severe threat to performance and r...

Intrinsically disordered regions (IDRs) play important roles in proteins that regulate gene expression. A prominent example is the intracellular domain of the Notch receptor (NICD), which regulates the transcription of Notch-responsive genes. The NICD sequence includes an intrinsically disordered RAM region and a conserved ankyrin (ANK) domain. The 111-residue RAM region mediates bivalent inter...

The root apical meristem (RAM) determines both RAM activity and the growth of roots. Plant roots are constantly exposed to adverse environmental stresses that can cause DNA damage or cell cycle arrest in the RAM; however, the mechanism linking root meristematic activity and RAM size to the DNA damage response (DDR) is unclear. Here, we demonstrate that a loss of function in RCC1/UVR8/GEF-Like 3...

Milena de Sousa Nascimento, Viviane Gianluppi Ferro & Ricardo Ferreira Monteiro Universidade Federal do Rio de Janeiro, Instituto de Biologia, Departamento de Ecologia, Laboratório de Ecologia de Insetos, CP 68020, 21941-590, Rio de Janeiro, RJ, Brazil. Universidade Federal de Goiás, Instituto de Ciências Biológicas, Departamento de Ecologia, 74690-900, Goiânia, GO, Brazil. Corresponding author...

BACKGROUND Shake flasks are widely used during the development of bioprocesses for recombinant proteins. Cultures of recombinant Escherichia coli with orbital mixing (OM) have an oxygen limitation negatively affecting biomass growth and recombinant-protein production. With the aim to improve mixing and aeration in shake flask cultures, we analyzed cultures subjected to OM and the novel resonant...

AbstPactAhfe RAM is RAM which has been made as reliable as a disk. W e coI1sider the problem of buffer management in partially safe buffers, i.e., butlers which contain both safe RAM and volatile RAM. Buffer managemnt techniques for partially safe buffers explicitly consider the safety of memory in deciding which data to place in the buffer, where to place it, and when to copy updaks back to th...