DNA:RNA hybrids, nucleic acid structures with diverse physiological functions, can disrupt genome integrity when dysregulated. Human telomeres were shown to form hybrids with the lncRNA TERRA, yet the formation and distribution of these hybrids among telomeres, their regulation and their cellular effects remain elusive. Here we predict and confirm in several human cell types that DNA:RNA hybrid...

Gregor Mendel's "Experiments on Plant Hybrids" (1865/1866), published 150 years ago, is without doubt one of the most brilliant works in biology. Curiously, Mendel's later studies on Hieracium (hawkweed) are usually seen as a frustrating failure, because it is assumed that they were intended to confirm the segregation ratios he found in Pisum Had this been his intention, such a confirmation wou...

A status of early series production of the barrel hybrids and modules of the ATLAS Semiconductor Tracker (SCT) is reported. 120 hybrids (with ASIC’s) and 98 modules were fabricated in Japan by the mid. August 2002 and gone through extensive quality assurance tests. Defective channels were found much less than 1% in hybrids and still less than 1% in modules. No increase of defective channels was...

While sexual selection is generally assumed to quickly cause or strengthen prezygotic barriers between sister species, its role in causing postzygotic isolation, through the unattractiveness of intermediate hybrids, is less often examined. Combining 24 years of pedigree data and recently developed species-specific molecular markers from collared (Ficedula albicollis) and pied (Ficedula hypoleuc...

A procedure has been developed for purifying specific mRNAs by hybridization to fragments of DNA and isolation of the hybrids by potassium iodide equilibrium buoyant density centrifugation. The hybrids obtained are essentially free of unhybridized RNA as well as double-stranded RNA. Moreover, the RNA in the hybrids is undamaged and can be translated in vitro. Application of this procedure to ma...

We report on hybrids of water-soluble calix[8]arenes and single-walled carbon nanotubes (SWCNTs); the hybrids formed supramolecular SWCNTs network polymer by adding guest dimer.

in order to study drought tolerance indices and to introduce tolerant maize hybrids in drought conditions, an experiment was conducted at the experimental field of seed and plant improvement institute, in 2009. the experiment was carried out using split-plot in a randomized complete block design (crbd) with three replications. the main plots consisted of three levels of irrigation regimes (irri...

to determine tetraploid pollinators resistant to cercospora leaf spot disease and bolting with optimum yield and quality, five tetraploid pollinators were crossed with a male sterile line, sb17. the hybrid seed was harvested from the male-sterile line. the hybrids together with four controls including resistant and susceptible cultivars (a total of 9 cultivars), were evaluated in a randomized c...

Field trials were conducted from 2007 to 2010 to compare grain fumonisin levels among non-Bt maize hybrids and Bt hybrids with transgenic protection against manual infestations of European corn borer (ECB) and Western bean cutworm (WBC). HPLC and ELISA were used to measure fumonisin levels. Results of the methods were highly correlated, but ELISA estimates were higher. Bt hybrids experienced le...

A series of mouse-human hybrids was prepared from mouse cells deficient in adenine phosphoribosyltransferase (EC 2.4.2.7) and normal human cells. The hybrids were made in medium containing adenine and alanosine, an antimetabolite known to inhibit de novo adenylic acid biosynthesis. The mouse cells, unable to utilize exogenous adenine, were killed in this medium, but the hybrids proliferated as ...