Hyaluronic acid fillers have become popular soft tissue filler augmentation agents over the past several years. They have helped revolutionize the filler market with a number of new products available for use for our patients. The purpose of this manuscript is to review the characteristics of the HA fillers and to review each of the current products currently available for use in the US.

background: vaginal atrophy is a common complication in menopause which does not improve with time and, if untreated, can affect the quality of life for women. the aim of this study was to compare the effectiveness of the vaginal cream of hyaluronic acid and conjugated estrogen (premarin) in treatment of vaginal atrophy. methods: this study was a randomized controlled clinical trial on 56 menop...

The efficacy of the application of botulinum toxin type A (BTX-A) and hyaluronic acid (HA) as minimally invasive treatments in facial rejuvenation has been previously demonstrated. The local side effects most frequently observed are pain, swelling, erythema, and bruising. In spite of the limited and benign nature of these events, they usually cause discomfort for the patient who is looking for ...

The hasA gene from Streptococcus equisimilis, which encodes the enzyme hyaluronan synthase, has been expressed in Bacillus subtilis, resulting in the production of hyaluronic acid (HA) in the 1-MDa range. Artificial operons were assembled and tested, all of which contain the hasA gene along with one or more genes encoding enzymes involved in the synthesis of the UDP-precursor sugars that are re...

Cultured human synovial cells secrete hyaluronic acid (HA) into the culture medium. Glucosamine-6-(3)H was shown to be a direct and relatively specific precursor of HA-(3)H by the following observations: the susceptibility of nondialyzable radioactivity in the medium to hyaluronidase, its migration with hexuronic acid on zone electrophoresis in polyvinyl chloride, its exclusion from Sephadex G-...

We present a novel strategy to fabricate anisotropic multicompartment Janus capsules by embedding larger containers into a soft poly-L-lysine/hyaluronic acid (PLL/HA) polymeric film, followed by adsorption of smaller containers on top of their unmasked surface. This research is also attractive for developing substrates for cell cultures.

15 An efficient method for the separation and recovery of Hyaluronic Acid (HA) from highly viscous broth was developed. In this strategy, the separation of HA from viscous culture broth and purification by optimizing different parameters, viz., temperature, pH, treatment with activated charcoal, were included. In addition, concentrating the HA solution using ultrafiltration facilitated the redu...

One important pharmacological function of hyaluronic acid (HA) in chondrocytes is reduction of cellular superoxide generation and accumulation. Here we demonstrated a relationship between HA supplementation and accumulation of Nuclear factor-erythroid-2-related factor 2 (Nrf2), which is a master transcription factor in cellular redox reactions, in cultured chondrocytes derived from bovine joint...

UNLABELLED BACKGROUND / OBJECTIVES: Hyaluronic acid (HA) is rarely described in dermatomyositis (DM). Thus, we determined any clinical association of serum levels of hyaluronic acid (HA) in patients with dermatomyositis (DM). MATERIALS AND METHODS This cross-sectional single-center analysis 75 DM and 75 healthy individuals, during the period from January 2012 to July 2013. An anti-HA antibody...

BACKGROUND Hyaluronic acid is a prognostic factor in ovarian cancers. It is also a component of Hyaluronic Acid-Carboxymethyl Cellulose (HA-CMC) barrier, an anti-adhesion membrane widely used during abdominal surgeries in particular for ovarian carcinosis. 70% of patients who undergo ovarian surgery will relapse due to the persistence of cancer cells. This study's objective was to determine the...