نتایج جستجو برای: humanized
تعداد نتایج: 6443 فیلتر نتایج به سال:
The overly-fast degradation rates of magnesium-based alloys in the biological environment have limited their applications as biodegradable bone implants. In this study, rare earth element yttrium (Y) was introduced into AZ61 magnesium alloy (Mg-6Al-1Zn wt %) to control the degradation rate by laser rapid melting. The results showed that the degradation rate of AZ61 magnesium alloy was slowed do...
BACKGROUND Monoclonal antibody therapeutics are rapidly gaining in popularity for the treatment of a myriad of diseases, ranging from cancer to autoimmune diseases and neurological diseases. Multiple forms of antibody therapeutics are in use today that differ in the amount of human sequence present in both the constant and variable regions, where antibodies that are more human-like usually have...
In this work we present a comprehensive study of the spectroscopic and thermo-optical properties of a set of samples with composition xNd(2)O(3)-(5-x)Y(2)O(3-)40CaO-55B(2)O(3) (0 ≤ x ≤ 1.0 mol%). Their fluorescence quantum efficiency (η) values were determined using the thermal lens technique and the dependence on the ionic concentration was analyzed in terms of energy transfer processes, based...
The low-lying electronic states of yttrium dicarbide have been calculated using highly correlated wave functions and systematic sequences of correlation consistent basis sets. For the (2)A(1) ground electronic state, the near-equilibrium potential energy surface (PES) has been calculated using the coupled cluster method in conjunction with basis sets ranging in size from double to quintuple zet...
Cold agglutinin disease is a rare autoimmune hemolytic anemia characterized by hemolysis that caused activation of the classic complement pathway. Sutimlimab, humanized monoclonal antibody, selectively targets C1s protein, C1 complex serine protease responsible for activating this
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