نتایج جستجو برای: human testicular stem cells

تعداد نتایج: 2741032  

Journal: :Development 2012
Cassy M Spiller Chun-Wei Feng Andrew Jackson Ad J M Gillis Antoine D Rolland Leendert H J Looijenga Peter Koopman Josephine Bowles

Germ cells, the embryonic precursors of sperm or oocytes, respond to molecular cues that regulate their sex-specific development in the fetal gonads. In males in particular, the balance between continued proliferation and cell fate commitment is crucial: defects in proliferation result in insufficient spermatogonial stem cells for fertility, but escape from commitment and prolonged pluripotency...

Journal: :Nucleic acids research 2003
Ann-Karin Olsen Nur Duale Magnar Bjørås Cathrine T Larsen Richard Wiger Jørn A Holme Erling C Seeberg Gunnar Brunborg

Oxidative damage in testicular DNA is associated with poor semen quality, reduced fertility and increased risk of stillbirths and birth defects. These DNA lesions are predominantly removed by base excision repair. Cellular extracts from human and rat testicular cells and three enriched populations of rat male germ cells (primary spermatocytes, round spermatids and elongating/elongated spermatid...

آتشی, امیر, ابراهیمی, لیلا, احمد بیگی, ناصر, امید خدا, آزاده, ذنوبی, زهرا, سلیمانی, مسعود, نیکو گفتار, مهین, کاویانی, سعید,

Background and Objective: Nowadays, although umbilical cord blood is a commonly used source of hematopoietic stem cell, its low frequency of these cells is the main factor limiting its clinical application. The transplantation of hematopoietic stem cells derived from placenta tissue along with umbilical cord blood cells of the same sample may be an appropriate approach to solve this problem. In...

ژورنال: حقوق پزشکی 2020

Stem cells are one of the most challenging areas of patent law as one of the important medical resources for the treatment of various diseases. The scope of this challenge relying on the legal approaches of countries depends on how to satisfy substantive requirments and moral considerations, especially in the field of embryonic stem cells. Accordingly, although such cells could be considered pa...

2009
Brad B Swelstad Candace L Kerr

Pluripotent stem cells have been derived from various embryonic, fetal and adult sources. Embryonic stem cells (ESCs) and parthenogenic ESCs (pESCs) are derived from the embryo proper while embryonic germ cells (EGCs), embryonal carcinoma cells (ECCs), and germ-line stem cells (GSC) are produced from germ cells. ECCs were the first pluripotent stem cell lines established from adult testicular t...

Behrang Alani, Mahdi Noureddini, Saeid Bagheri-Mohammadi,

Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by motor and non-motor symptoms. It is expected to impose an increasing economic and social burden on human populations. The motor symptoms of PD are well known, including age-dependent uncontrollable resting tremor, bradykinesia, rigidity, posture instability. In the non-motor symptoms, cognitive changes, d...

Journal: :dental research journal 0

dental tissues provide an alternate source of stem cells compared with bone marrow and have a similar potency as that of bone marrow derived mesenchymal stem cells. it has been established there are six types of dental stem cells: dental pulp stem cells, stem cells from human exfoliated deciduous teeth, stem cells from apical papilla, periodontal ligament stem cells, dental follicle progenitor ...

Farah Zaker, Masoud Soleimani, Mohammad Hossein Tahmasbi, Mohammad Taghi Joghataei, Seyed Akbar Moosavi, Seyed Amir Yazdanparast,

New blood forming vessels are produced by differentiation of mesodermal precursor cells to angioblasts that become endothelial cells (ECs) which in turn give rise to primitive capillary network. Human cord blood (HCB) contains large subsets of mononuclear cells (MNCs) that can be differentiated into endothelial-like cells in vitro. Human mononuclear progenitor cells were purified from fresh umb...

Introduction:  Monthly regeneration of endometrium after cyclical mensturation confirmed the ability of specific population of the cells that presence in the basalis layer and undergone consecutive hormonal changes that could prepared the endometrial layer for probable implantation. These cells, known as, stem cell. The aim of this study was the isolation and culture of human endometrial derive...

Ahmadi Rastegar D Alikhani M Arefnezhad B Baharvand H Ebrahimi M Gourabi H Hosseini Salekdeh Gh, Jangravi Z Karamzadeh R Mirshahvaladi Sh Mohseni Meybodi A Moosavi-Movahedi AA Mousavi SA Nasr-Esfahani MH Parsa Matin P Pooyan P Sabbaghian M Sedighi Gilani MA Shahhoseini M Sharifi Tabar M Taleahmad S Vakilian H

The major goal of the Chromosome-Centric Human Proteome Project (C-HPP) is to systematically map the entire human proteome with the intent to enhance our understanding of human biology at the cellular level. However, this goal may be hindered by the lack of quality observations of given proteins due to absence of expression in a given tissue, very low abundance, and expression only in rare samp...

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