نتایج جستجو برای: human papillomavirus 18
تعداد نتایج: 1942608 فیلتر نتایج به سال:
Previous work with primary human keratinocytes demonstrated that quercetin, a potent mutagen found in high levels in bracken fern (Pteridium aquilinum), arrested cells in G1 with concomitant elevation of the cyclin-dependent kinase inhibitor (cdki) p27Kip1. Expression of the human papillomavirus type 16 (HPV-16) E6 and E7 oncoproteins, under transcriptional control of a heterologous promoter, i...
To determine the etiology of combined high-grade squamous intraepithelial lesion (HSIL) and adenocarcinoma in situ (AIS) of the uterine cervix, we examined human papillomavirus (HPV) subtypes, methylation status of the HPV-16 L1 gene, and immunohistochemical staining pattern of Krt7 in 8 cases of combined HSIL and AIS. Overall, 6 (75%) of 8 patients with combined HSIL and AIS were infected by t...
Cervical cancer is one of the most common cancers in women globally and is responsible for the large percentage of women’s death in developing countries. Epidemiological and laboratory data have shown that persistent infection with oncogenic human papillomavirus (HPV), particularly HPV-16 and HPV-18, is the main risk factor, but not solely responsible for the development of cervical cancer. Oth...
IMPORTANCE Global use of human papillomavirus (HPV) vaccines to prevent cervical cancer is impeded by cost. A 2-dose schedule for girls may be possible. OBJECTIVE To determine whether mean antibody levels to HPV-16 and HPV-18 among girls receiving 2 doses was noninferior to women receiving 3 doses. DESIGN, SETTING, AND PATIENTS Randomized, phase 3, postlicensure, multicenter, age-stratified...
BACKGROUND HPV burden is a predictor for high-grade cervical intraepithelial neoplasia and cancer. The natural history of HPV load in young women being recently exposed to HPV is described in this paper. METHODS A total of 636 female university students were followed for 2 years. Cervical specimens with HPV-16, -18, -31, or -45 DNA by consensus PCR were further evaluated with type-specific an...
Abstract Background and Objective: Ophthalmic pterygium is a potentially vision-threatening lesion of unknown etiology that often extends on the corneal surface and has a worldwide distribution. Despite various studies, the pathogenesis of pterygium remains unclear and the involvement of human papillomavirus is controversial. We aimed to investigate the involvement of papillomavirus in pte...
BACKGROUND An epidemic of human papillomavirus (HPV)-related oropharyngeal squamous cell cancer (OPSCC) has been reported worldwide largely due to oral infection with HPV type-16, which is responsible for approximately 90% of HPV-positive cases. The purpose of this study was to determine the rate of HPV-positive oropharyngeal cancer in Southwestern Ontario, Canada. METHODS A retrospective sea...
results human papillomavirus was found in 62.1% of the samples obtained from the patients. among the hr and lr types, hpv-6 was the major genotype 64.8%. type 16 and 18 were the most frequent hr-hpv types (presented in 26% of the patient), followed by type 50s (24.7%), 45, 30s, and 11 (1.8% from each). multiple hpv infections were presented in 40.7% of the positive genotyping specimens. backgro...
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