background: perioglasâ (pg) is an alloplastic material used for grafting periodontal osseous defects since 1995. in animal models, it has been proven that pg achieves histologically good repair of surgically created defects. in clinical trials, pg was effective as an adjunct to conventional surgery in the treatment of intrabony defects. because the molecular events due to pg that are able to al...

Introduction: Mechanical stimulation of human mesenchymal stem cells has demonstrated changes in many cell behaviours such as adhesion, migration, growth and differentiation through mechanotransductive pathways. These include experiments on effect of nanotopography 1, shear stress, stiffness of extracellular matrix 2, strain, stress and acoustic wave energy 3 on cells. In this research we wer...

This study proposes the use of carbon nanotubes (CNTs) as reinforcement to enhance the mechanical properties of a polylactide-caprolactone copolymer (PLC) matrix. Biological interaction of PLC-CNT composites with human osteoblast cells is also investigated. Addition of 2 wt % CNT shows very uniform dispersion in the copolymer matrix, whereas 5 wt % CNT shows severe agglomeration and high porosi...

The treatment process for healing fractures in the community is still mostly done through traditional methods, which are generally referred to as "sangkal putung". results obtained 28.2% can not return its original form. In of denying putung it takes quite a long time depending on part bone that has broken. This study aims reveal potential effect exposure ELF (Extremely Low Frequency) magnetic ...

Abstract Introduction The in vitro expansion and differentiation of mesenchymal stem cells derived from bone marrow (BM-hMSCs) are considered as potential therapeutic tools for clinical applications tissue engineering regenerative medicine. However, invasive sampling reduction number proliferative capacity with age the major limitations BM-hMSCs. Recently, human placenta-derived MSCs (PL-hMSCs)...

PURPOSE Cabozantinib, an orally available multityrosine kinase inhibitor with activity against mesenchymal epithelial transition factor (MET) and VEGF receptor 2 (VEGFR2), induces resolution of bone scan lesions in men with castration-resistant prostate cancer bone metastases. The purpose of this study was to determine whether cabozantinib elicited a direct antitumor effect, an indirect effect ...

BACKGROUND/AIMS Proliferation and differentiation of osteoblast-like cells are regulated by complex interactions among systemic hormones, cytokines, and local growth factors. The success of oral rehabilitation using biomaterial implants depends on the growth of osteoblasts and their adhesivity to the surface of the implant. The study aimed to investigate the effect of different growth factors o...