Hydrogels prepared from a bacterial fimbriae are utilized for the 2D cell culture of human dermal fibroblasts. The tunable biochemical and mechanical nature Caf1 hydrogels allow modulation morphology matrix deposition.

Background. Oral submucous fibrosis (OSF), a precancerous condition, is characterized by abnormal accumulation of collagen fibers in oral submucosa. Vimentin is a Class 2 intermediate filament (IF) and primarily expressed in cells of mesenchymal origin. Vimentin is also found to be involved in cell growth, cell cycling, and tumour differentiation. Objective. The purpose of the study was to comp...

Advances in cell culture methods, multidisciplinary research, clinical need to replace lost skin tissues and regulatory need to replace animal models with alternative test methods has led to development of three dimensional models of human skin. In general, these in vitro models of skin consist of keratinocytes cultured over fibroblast-populated dermal matrices. Accumulating evidences indicate ...

Neurofibromas are uncommon benign tumors in the oral cavity, which composed of Schwann cells, perineural-like and fibroblasts. The diagnosis can be confirmed by histological examination immunopositivity for S-100 protein indicating its neural origin. Surgical excision is treatment choice, intraoral approach best route a medium-sized lesion prognosis excellent. This paper aims at to present unus...

Kaposi's sarcoma (KS) remains the most common tumor arising in patients with HIV/AIDS, and involvement of the oral cavity represents one of the most common clinical manifestations of this tumor. HIV infection incurs an increased risk for periodontal diseases and oral carriage of a variety of bacteria. Whether interactions involving pathogenic bacteria and oncogenic viruses in the local environm...

Electronic-cigarettes (e-cigs) represent a significant and increasing proportion of tobacco product consumption, which may pose an oral health concern. Oxidative/carbonyl stress via protein carbonylation is an important factor in causing inflammation and DNA damage. This results in stress-induced premature senescence (a state of irreversible growth arrest which re-enforces chronic inflammation)...

This in vitro study evaluated the biocompatibility and abrasivity of whitening conventional toothpastes. Samples (non-whitening) - Edel White Infant (EWI) toothpastes Whitening (EWW), CAREFORTE (EWC), Colgate Total 12 Ò Professional (C), Oral-B (OB) were dissolved culture medium (0.2 g sample weight per mL). Human gingival fibroblasts (hGF) placed contact with different dilutions media that had...