A hand-foot-mouth disease outbreak occurred in 2014 around Guangdong. The purpose of this study was investigating the status and susceptibility of infectious neutralizing antibodies to enterovirus 71 among children so as to provide scientific evidence for the population immunity level of hand-foot-mouth disease and prepare for enterovirus 71 vaccination implementation. Serum specimens were coll...

We report the case of an eight-month-old girl who presented with a poliomyelitis-like paralysis in her left upper limb caused by enterovirus 71 infection. She recovered useful function after nerve transfers performed six months after the onset of paralysis. Early neurotisation can be used successfully in the treatment of poliomyelitis-like paralysis in children.

Enterovirus 71 (HEV7l) is a non-enveloped, single stranded positive sense RNA virus belonging to the genus Enterovirus of the Picornaviridae family. HEV71 is an important causative agent of hand, foot and mouth disease (HFMD) worldwide affecting millions of young children annually'. The pathogenesis of HEV71 infection however, is not well established. It is not known for example why the infecti...

As a predominant cause of human hand, foot, and mouth disease, enterovirus 71 (EV71) infection may lead to serious diseases and result in severe consequences that threaten public health and cause widespread panic. Although the systematic identification of physical interactions between viral proteins and host proteins provides initial information for the recognition of the cellular mechanism inv...

Enterovirus 71 is reported to have emerged in Cambodia in 2012; at least 54 children with severe encephalitis died during that outbreak. We used serum samples collected during 2000-2011 to show that the virus had been widespread in the country for at least a decade before the 2012 outbreak.

During an Outbreak of Hand, Foot, and Mouth Disease in Shandong, China To the Editor—Hand, foot, and mouth disease (HFMD) is caused by human enteroviruses, most frequently human enterovirus 71 (HEV-71) and coxsackievirus A16 (CV-A16). Other viruses (CV-A4 to A7, A9, A10, A24, and B2 to B5; echoviruses 1, 4, 11, and 18; and HEV-18) may also be associated with HFMD outbreaks or sporadic cases. HF...