نتایج جستجو برای: htra1

تعداد نتایج: 528  

Journal: :Journal of experimental botany 2005
Peter J Nixon Myles Barker Marko Boehm Remco de Vries Josef Komenda

A common feature of light stress in plants, algae, and cyanobacteria is the light-induced damage to the photosystem II complex (PSII), which catalyses the photosynthetic oxidation of water to molecular oxygen. A repair cycle operates to replace damaged subunits within PSII, in particular, the D1 reaction centre polypeptide, by newly synthesized copies. As yet the molecular details of this physi...

Journal: :Vision Research 2010
Alexandra C. Silveira Margaux A. Morrison Fei Ji Haiyan Xu James B. Reinecke Scott M. Adams Trevor M. Arneberg Maria Janssian Joo-Eun Lee Yang Yuan Debra A. Schaumberg Maria G. Kotoula Evangeline E. Tsironi Aristoteles N. Tsiloulis Dimitrios Z. Chatzoulis Joan W. Miller Ivana K. Kim Gregory S. Hageman Lindsay A. Farrer Neena B. Haider Margaret M. DeAngelis

To identify novel genes and pathways associated with AMD, we performed microarray gene expression and linkage analysis which implicated the candidate gene, retinoic acid receptor-related orphan receptor alpha (RORA, 15q). Subsequent genotyping of 159 RORA single nucleotide polymorphisms (SNPs) in a family-based cohort, followed by replication in an unrelated case-control cohort, demonstrated th...

Journal: :Enfermedades infecciosas y microbiologia clinica 2013
Sonia Santibáñez Aránzazu Portillo Paula Santibáñez Ana M Palomar José Antonio Oteo

BACKGROUND The effectiveness of PCR methods to amplify rickettsiae from clinical samples has still not been evaluated. Our aim was to determine the sensitivity and usefulness for Rickettsia species identification by PCR methods, targeting 16S rDNA, htrA, gltA, ompA, and ompB genes for molecular diagnosis of rickettsioses. METHODS A total of 72 clinical samples (EDTA-blood, skin biopsies and t...

Journal: :Journal of Histochemistry & Cytochemistry 2003

Journal: :Acta Crystallographica Section A Foundations of Crystallography 2005

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Qing-Tao Shen Xiao-Chen Bai Lei-Fu Chang Yi Wu Hong-Wei Wang Sen-Fang Sui

In the periplasm of Escherichia coli, DegP (also known as HtrA), which has both chaperone-like and proteolytic activities, prevents the accumulation of toxic misfolded and unfolded polypeptides. In solution, upon binding to denatured proteins, DegP forms large cage-like structures. Here, we show that DegP forms a range of bowl-shaped structures, independent of substrate proteins, each with a 4-...

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