The mammalian b-globin locus is a multigenic, developmentally regulated, tissuespecific locus from which gene expression is regulated by a distal regulatory region, the locus control region (LCR). The functional mechanism by which the b-globin LCR stimulates transcription of the linked b-like globin genes remains unknown. The LCR is composed of a series of 5 DNaseI hypersensitive sites (5*HSs) ...

In [1], Gu and Tian [Chuanqing Gu, Zhaolu Tian, On the HSS iteration methods for positive definite Toeplitz linear systems, J. Comput. Appl. Math. 224 (2009) 709–718] proposed the special HSS iteration methods for positive definite linear systems Ax = b with A ∈ Cn×n a complex Toeplitz matrix. But we find that the special HSS iteration methods are incorrect. Some examples are given in our paper.

This paper is concerned with a generalization of the Hermitian and skew-Hermitian (HSS) splitting iteration for solving positive definite, non-Hermitian linear systems. It is shown that the new scheme can outperform the standard HSS method in some situations and can be used as an effective preconditioner for certain linear systems in saddle point form. Numerical experiments using discretization...

Abstract Heart sound segmentation (HSS) aims to detect the four stages (first sound, systole, second heart and diastole) from a cycle in phonocardiogram (PCG), which is an essential step automatic auscultation analysis. Traditional HSS methods need manually extract features before dealing with tasks. These artificial highly rely on extraction algorithms, often result poor performance due differ...

Friction surfacing is an emerging surface engineering technology, developed on the basic principle of friction welding, for depositing wear and corrosion resistant metallic coatings. In the present work coating of tool steel M2 were made on mild steel by friction surfacing by using 2 factorial designs with 3 factors at two levels for each. Process parameters developed a satisfactory deposition ...

This paper describes sixteen fire tests conducted on slender circular hollow section columns filled with normal and high strength concrete, subjected to concentric axial loads. The test parameters were the nominal strength of concrete (30 and 80 MPa), the infilling type (plain concrete, reinforced concrete and steel fiber reinforced concrete) and the axial load level (20% and 40%). The columns ...

The automotive industry is using more and more of Advanced High Strength Steel in order to reduce the weight of the car. Since this will generate more springback, it is of vital importance to be able to predict the amount of springback in the parts. Otherwise, many late changes have to be made in order to fit the parts in their position. In order to increase the ability to understand and test t...

The major needs in machining are high material removal rate, good work surface finish and low tool wear. These objectives can be achieved by reducing tool wear using proper cutting fluid during machining.The effect of some cutting fluids namely: Mentholated spirit, paraffin, and soluble oil on the flank wear of High-speed steel and carbide tipped tools by orthogonal cutting has been studied. Ce...

Stevens-Johnson syndrome (SJS) and drug-induced hypersensitivity syndrome (HSS, also known as DRESS) are life-threatening drug hypersensitivity reactions. Previous studies on genetic predictors for SJS and HSS were focused on immune-related genes and on known, frequent polymorphisms in the genome. For the anticonvulsant carbamazepine (CBZ), genetic markers for CBZ-induced SJS and HSS have been ...