The expression of the M, 70,000 heat shock protein (HSP-70) in heatresistant variants or heat-shocked cells has been correlated with devel opment of thermal resistance. In these studies polymerase chain reaction (PCR) was used to detect low levels of HSP-70 mRNA present in control, unheated cells to investigate the possibility of predicting the intrinsic heat response in various leukemic cells....

Subcellular fractionation and immunofluorescence microscopy have been used to study the intracellular distributions of the major heat shock proteins, hsp 89, hsp 70, and hsp 24, in chicken embryo fibroblasts stressed by heat shock, allowed to recover and then restressed. Hsp 89 was localized primarily to the cytoplasm except during the restress when a portion of this protein concentrated in the...

BACKGROUND Henoch-Schönlein purpura (HSP) is the most common vasculitis in childhood. Severe central nervous system (CNS) involvement is rare in HSP. CASE CHARACTERISTICS Three children with features of HSP presented with seizures and CNS dysfunction. OBSERVATION All three children had abnormalities on neuroimaging; 2 had complete remission but one was left with severe neurological damage. ...

Homeostatic synaptic plasticity (HSP) is an important mechanism attributed with the slow regulation of the neuron's activity. Whenever activity is chronically enhanced, HSP weakens the weights of the synapses in the dendrites and vice versa. Because dendritic morphology and its electrical properties partition the dendritic tree into functional compartments, we set out to explore the interplay b...

We investigated analytically and numerically the interplay between two opposing forms of synaptic plasticity: positive-feedback, long-term potentiation/depression (LTP/LTD), and negative-feedback, homeostatic synaptic plasticity (HSP). A detailed model of a CA1 pyramidal neuron, with numerous HSP-modifiable dendritic synapses, demonstrates that HSP may have an important role in selecting which ...

Xenopus cells express two major proteins on heat shock, designated hsp 70 and hsp 30. Several cDNA clones for the corresponding mRNAs were identified and sequenced. Inducibility and abundance of heat shock mRNAs in various cell types and developmental stages was determined by nuclease S1-mapping. The only cells found to contain hsp 70 mRNA without heat shock are the oocytes. The level of this s...

The term “Highly Sensitive Person” (HSP) refers to an individual’s temperament. They have common characteristics with attention-deficit/hyperactivity disorder and other, their central feature is a high empathy. However, the questionnaires may be inaccurate because they depend on examinee’s self-perception. Conversely, emotional empathy activation of mirror neurons are as HSP. We thought quantit...

This paper studies acoustic emission (AE) wave propagation in a glass fibre aluminium honeycomb sandwich panel (HSP). Of particular novelty is the quantification of through-thickness AE from one surface HSP to other, which real-world monitoring consideration for applications where instrumentation only be permissible on surface, i.e. aerofoils. Complexity was introduced specimens stages enable t...

Hereditary spastic paraplegia (HSP) is a cluster of genetically heterogeneous disorders that has spastic paraplegia as the central feature. Autosomal dominant HSP (AD-HSP) is also genetically heterogeneous and seven loci have been identified so far on chromosomes 14q (SPG3), 2p (SPG4), 15q (SPG6), 8q (SPG8), 12q (SPG10), 19q (SPG12), and 2q (SPG13). Among them, the SPG4 gene named spastin (GenB...