Antimicrobial activity and the properties of edible film were studied by incorporating with encapsulated clove (Eugenia caryophyllata Thunb.) oil as a natural antibacterial agent. The minimal bactericidal concentration (MBC) of clove oil inhibited the growth of E. coli O175:H7, S. aureus and L. monocytogenes were tested in the stationary phase. The results showed that 1.0, 1.5 and 0.5% of clove...

Abstract The main aim of this study was to prepare and evaluate the extended - release system of an anxiolytic substance. Alprazolam is a short-acting benzodiazepine with general properties similar to those of diazepam. Our studies focused on the development of extended drug delivery system based on Hydroxy Propyl Methyl Cellulose (HPMC 4000cps) as retard agent and polyvinylpyrrolidone (PVP k30...

161 Abstract: Pulsatile systems are best for the drugs, which follows chronopharmacological behaviour where night time dosing is required, drugs having high first-pass effect and having specific site of absorption in GIT. In this study, colon targeted pulsatile release tablets of atenolol was prepared using press coating technique to treat hypertension in the early hours of the morning. Pulsati...