Clinical question " What treatments are available for hot flushes in women receiving tamoxifen? " A 62-year-old woman asked her radiation oncologist this question. She was taking tamoxifen as adjuvant treatment for node-positive breast cancer, but was experiencing persistent and frequent hot flushes. The search question was refined to " What treatments can be added to tamoxifen to reduce the fr...

To determine the incidence rate of seborrheic dermatitis, bullous pemphigoid, rosacea, and melanoma among patients diagnosed with Parkinson's Disease. A cross-sectional, observational study. From 13th May 2020 to April 2022 at Bahria International Hospital, Lahore, Pakistan. total 80 confirmed disease were evaluated for skin disorders. Disease severity was through Hoehn Yahr staging criteria (H...

Facial flushing and sweating were investigated in five patients who complained of the sudden onset of unilateral facial flushing in hot weather or when exercising vigorously. One patient probably suffered a brainstem infarct at the time that the unilateral flush was first noticed, and was left with a subtle Horner's syndrome on the side opposite to the flush. The other four had no other neurolo...

Corresponding author: Sung Ha Mun, M.D., Department of Anesthesiology and Pain Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108, Pyoung-dong, Jongro-gu, Seoul 110-746, Korea. Tel: 82-2-2001-2001, Fax: 82-2-2001-2326, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License...

A 49-year-old perimenopausal woman, gravida 7, para 5 was referrred to our gynecology clinic for the evaluation of extensive ascites. From her history we learned that she had been admitted to the rheumatology clinic with complaints of arthalgia and fatigue 2 months previously and had been given salazopyrin therapy for the past 2 months with a presumptive diagnosis of rheumatoid or infective art...

An investigation of malaria in a US patient without recent travel established Plasmodium falciparum molecular genotype identity in 2 patients who shared a hospital room. P. falciparum can be transmitted in a hospital environment from patient to patient by blood inoculum if standard precautions are breached.

In this issue of Blood, Dutt and colleagues address the selective effect of ribosomal protein haploinsufficiency on erythroid development observed in congenital Diamond-Blackfan anemia (DBA) and acquired 5q-syndrome. Their findings reveal a selective induction of p53 in the erythroid lineage in response to reduced expression of ribosomal proteins affected in these diseases. Moreover, the select...