Improving quality and safety across an entire healthcare system in multiple clinical areas within a short time frame is challenging. We describe our experience with improving inpatient quality and safety at Kaiser Permanente Northern California. The foundations of performance improvement are a "four-wheel drive" approach and a comprehensive driver diagram linking improvement goals to focal area...

ObjectivesTo describe the burden, epidemiology and outcomes of co-infections superinfections occurring in hospitalized patients with coronavirus disease 2019 (COVID-19).MethodsWe performed an observational cohort study all consecutive admitted for ≥48 hours to Hospital Clinic Barcelona COVID-19 (28 February 22 April 2020) who were discharged or dead. We demographic, epidemiologic, laboratory mi...

INTRODUCTION To identify patient characteristics associated with low serum 25-hydroxyvitamin D (25(OH)D) concentrations in the medical intensive care unit (ICU) and examine the relationship between serum 25(OH)D and the risk for hospital-acquired infections. METHODS This is a prospective observational cohort of adult patients admitted to the medical ICU at an urban safety net teaching hospita...

background and aims: acinetobacter baumannii is mostly a cause of septicaemia, pneumonia and urinary tract infections following hospitalization of patients with more severe illnesses. the aim of this study was to determine the prevalence and detection of the most prevalent virulence genes in a. baumannii isolated from hospital infections of two largest hospitals of tehran, iran. materials and m...

objective to investigate association between nosocomial infection, blood products transfusion and microorganisms responsible in patients who hospitalized at icu (intensive care unit). patients and methods in this prospective study, 217 patients who were admitted to the icu of taleghani hospital between august 2010 and august 2011 were included. nosocomial infections were defined using the conta...

The emergence of multidrug-resistant Acinetobacter baumannii is a major concern to healthcare providers and facilities in many parts the world. This bacterial pathogen commonly implicated hospital-acquired infections, particularly critically ill patients admitted intensive care unit (ICU). extensive use antibiotics, ICUs, lack proper infection control interventions hospitals have led an increas...

BACKGROUND Results of previous single-center, observational studies suggest that daily bathing of patients with chlorhexidine may prevent hospital-acquired bloodstream infections and the acquisition of multidrug-resistant organisms (MDROs). METHODS We conducted a multicenter, cluster-randomized, nonblinded crossover trial to evaluate the effect of daily bathing with chlorhexidine-impregnated ...