1 Universidad del Valle. Hospital Universitario del Valle. Department of Internal Medicine. Cali, Colombia. 2 Universidad del Valle and Universidad Libre. Hospital Universitario del Valle, Department of Internal Medicine. Cali, Colombia. 3 Universidad Libre, Department of Internal Medicine. Cali, Colombia. 4 Universidad del Valle. Hospital Universitario del Valle, Department of Pathology. Cali,...

Caspase-8 (encoded by the CASP-8 gene) is crucial in generating cell death signals and eliminating potentially malignant cells. Genetic variation in CASP8 may affect susceptibility to cancer. The CASP-8 -652 6N ins/del (rs3834129) polymorphism has been previously reported to influence the progression to several cancers. However, the overall reported studies have shown inconsistent conclusions. ...

A few genetic polymorphisms of TP53 are known to have a significant effect on cancer susceptibility. Intron 3 16 bp duplication polymorphism of TP53 has been reported to be associated with breast cancer, colorectal cancer, lung cancer and other cancers, but the reported results remain inconclusive. The present study, a meta-analysis including a total of 9801 cases and 10,391 controls from 26 st...

Título: Un enfoque socio-perceptivo/ecológico del desarrollo léxico: Affordances del contexto comunicativo. Resumen: Los supuestos básicos cruciales de la posición innatista influyen en los investigadores hasta hacerles ignorar la fuente del input linguistico, sus características y su impacto sobre el desarrollo del lenguaje. Sin embargo, un supuesto fundamental del enfoque socio-perceptivo/eco...