When submitted to a visuomotor rotation, subjects show rapid adaptation of visually guided arm reaching movements, indicated by a progressive reduction in reaching errors. In this study, we wanted to make a step forward by investigating to what extent this adaptation also implies changes into the motor plan. Up to now, classical visuomotor rotation paradigms have been performed on the horizonta...

PURPOSE The effects of paralytic strabismus on the vestibulo-ocular reflex (VOR) have not been systematically investigated in humans. The purpose of this study was to analyze the VOR in patients with unilateral peripheral sixth nerve palsy. METHODS Twenty-one patients with unilateral peripheral sixth nerve palsy (6 severe, 7 moderate, 8 mild) and 15 normal subjects were studied. Subjects made...

The Journal of Clinical Pediatric Dentistry Volume 25, Number 2/2000 147 INTRODUCTION The craniomandibular system is designed to function as a unit and its parts cannot be considered independently. The idea of a malfunctioning unit is reflected in the term, craniomandibular disorders, (CMD) which is a collective term embracing a number of clinical problems that involves the masticatory musculat...

An ionic current model of the retinal horizontal cell is constructed. The horizontal cell models are interconnected by gap junctions to form a horizontal cell layer. The light response properties of the L-type horizontal cell are analyzed using this model. We demonstrate the functional role of each ionic current and the role of the feedback loop between cones and horizontal cells. The present s...

We describe a stochastic birth-and-death model of evolution of horizontally transferred genes in microbial populations. The model is a generalization of the stochastic model described by Berg and Kurland and includes five parameters: the rate of mutational inactivation, selection coefficient, invasion rate (i.e., rate of arrival of a novel sequence from outside of the recipient population), wit...

An important issue in neuroscience is the effect of visual loss on the remaining senses. Two opposing views have been advanced. On the one hand, visual loss may lead to compensatory plasticity and sharpening of the remaining senses. On the other hand, early blindness may also prevent remaining sensory modalities from a full development. In the case of sound localization, it has been reported re...

INTRODUCTION Thyroid orbitopathy is the most common cause of restrictive strabismus. Patients often present with vertical or horizontal double vision, or both, due to restriction involving most commonly the inferior and medial rectus muscles. Traditional muscle surgery involves release of the tight muscles. Previous literature has described a frequent need for secondary operations and an overco...

Mammals contain 1 melanopsin (Opn4) gene that is expressed in a subset of retinal ganglion cells to serve as a photopigment involved in non-image-forming vision such as photoentrainment of circadian rhythms. In contrast, most nonmammalian vertebrates possess multiple melanopsins that are distributed in various types of retinal cells; however, their functions remain unclear. We previously found ...

Our goal is to link spatial and temporal properties of letter recognition to reading speed for text viewed centrally or in peripheral vision. We propose that the size of the visual span the number of letters recognizable in a glance imposes a fundamental limit on reading speed. and that shrinkage of the visual span in peripheral vision accounts for slower peripheral reading. In Experiment 1, we...