OBJECTIVE This study examines the usefulness of childhood glucose homeostasis variables (glucose, insulin, and insulin resistance index [homeostasis model assessment of insulin resistance {HOMA-IR}]) in predicting pre-diabetes and type 2 diabetes and related cardiometabolic risk factors in adulthood. RESEARCH DESIGN AND METHODS This retrospective cohort study consisted of normoglycemic (n = 1,0...

conclusions it seems that hp eradication per se might not affect lfc, lft, lipid profile, and insulin resistance in dyspeptic nafld patients. results one hundred (49 males) patients with the mean age of 43.46 (± 11.52) were studied. repeated measure anova showed a significant reduction in lfc, anthropometric measurements, and laboratory parameters (except for hdl) in the both groups during the ...

background: bilateral salpingo-oophorectomy in women may lead to metabolic consequences in patients. this study was performed to determine the glucose tolerance and lipid profile after menopause resulting from bilateral salpingo-oophorectomy. methods: from september 2011 to march 2013, 31 women participants aged 46-52 years who underwent hysterectomy and bilateral salpingo-oophorectomy for beni...

background: we investigated the effects of withania somnifera root (ws) on insulin resistance, tumor necrosis factor α (tnf-α), and interleukin-6 (il-6) in fructose-fed rats. methods: forty-eight wistar-albino male rats were randomly divided into four groups (n=12); group i as control, group ii as sham-treated with ws by 62.5mg/g per diet, group iii fructose-fed rats received 10%w/v fructose, a...

background there are several studies in the literature investigating factors which can induce non-alcoholic fatty liver disease (nafld) in different populations. however, the existing literature lacks powerful studies addressing the factors which may predict the severity of nafld. objectives in the current study, we aimed to evaluate factors independently associated with liver echogenicity in a...