Procedures for impact assessment, including “beyond-BACI” (before–after control–impact) and proportional differences (ratios between impact and control treatments) were used to test population replenishment of marine invertebrates at a marine conservation area (MCA) and three fished (control) areas in the Solomon Islands of the southwestern tropical Pacific. Within shallow reef terrace habitat,...

Two new triterpene glycosides, scabraside A (1) and B (2), and a structurally known compound (3), were isolated from the sea cucumber Holothuria scabra (Holothuriidae) collected from the South China Sea. Structure of these compounds was elucidated by spectroscopic and chemical methods. The glycosides 1 and 2 exhibit the same common structural features, i. e., the presence of 12- and 17-hydroxy ...

conclusions our results suggest that h. parva and h. oculata may be promising therapeutic candidates for the treatment of hcc, following further confirmatory in vivo experiments and clinical trials. results our results showed that h. parva methanolic extracts (250, 500, and 1000 µg/ml) and h. oculata methanolic extracts (200, 400, and 800 µg/ml) increased reactive oxygen species (ros) formation...

The understanding of the distribution and population structure various species in marine environment is very helpful to effectual resource management conservation. This study aimed assess ecological factors relating sea cucumber populations on rocky shores Persian Gulf. Population two were investigated along 6 intertidal sites, including Deylam, Bushehr, Dayer, Nayband, Bostaneh, Lengeh Bushehr...

Immunostimulant is a substance that can stimulate the immune system against pathogenic microbes. Natural products produced by sea cucumbers have potential to be developed as immunostimulants. This study was aimed evaluate imunostimulatory activity of Holothuria atra extract using phagocytocyte assay macrophage cells and differentiation leukocyte in rats. The samples H. were taken from Halmahera...

The sea cucumber Holothuria scabra is an endangered species. In this study, nine new polymorphic microsatellite loci were developed and tested in 30 individuals. The number of alleles ranged from 2 to 5, and the observed and expected heterozygosities ranged from 0.1200 to 0.7391 and from 0.2408 to 0.5983, respectively. No loci significantly deviated from the Hardy-Weinberg equilibrium af-ter a ...

We have previously characterized the first invertebrate homolog of serum amyloid A (SAA) proteins in the sea cucumber Holothuria glaberrima, where its expression is associated with intestinal regeneration, suggesting a possible involvement of SAA proteins in intestinal morphogenesis. Here we show that bacterial lipopolysaccharides (LPS) trigger a coelomocyte-mediated immune response in H. glabe...

Research on the involvement of retroelements in developmental processes has been gaining momentum recently; however, most of the studies published so far have been focused on embryonic development. This commentary presents two recent papers, which document significant changes in transcriptional activity of retroelements in two different model systems, salamander limb regeneration and regenerati...