In order to respond to the problem of urban decline, different approaches have been defined in sucha way that urban regeneration approach became current in the 1980s (and more wildly after 1995) as a replacement for urban renewal. Urban regeneration is the holistic process of reversing economic, social and physical decay in areas where it has reached a stage when market forces alone will not su...

For the planning of large infrastructure projects, such as tunnelled inner-city carriageways, completely different scales have to be considered – ranging from the scale of several kilometres for the general routing of the carriageway down to centimetre scale for the detailed planning of track nodes. However, today’s planning software hardly supports multi-scale approaches. The paper presents a ...

Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales. In this manuscript we review mathematical modelling approaches used to describe the individual spatial scales and how they are integrated into holistic models. We discuss the ...