BACKGROUND Extra nodal and extra lymphatic propagation of Hodgkin's disease is a characteristic of the fourth stage of disease when the organs are affected. Primary appearances of the disease outside the lymph node is a rare event. Therefore, it makes diagnostic problem. Skeletal system is possible localization of primary extra nodal Hodgkin's disease. CASE REPORT Women, 42-years-old, was adm...

Background: China is facing the aggravating disease burden of lymphoma. However, accurate information about lymphoma at national and provincial levels limited. Methods: Following general analytical strategy used in Global Burden Diseases, Injuries, Risk Factors Study 2019, age-, sex- province-specific incidence, mortality prevalence Hodgkin (HL) non-Hodgkin (NHL) were analyzed. Lymphoma was ass...

Primary cutaneous lymphomas rank as the second most common clinical form of extranodal non-Hogdkin malignant lymphomas. Among non-Hodgkin skin T-cell lymphomas, Mycosis Fungoides (MF) is frequent occurence. The MF lymphoma originates in skin-homing helper T-cells, which express CD4 + marker, showing chronic evolution, with recurrent lesions. In advanced stages, patients may experience severe/ex...

In this review we present contemporary understanding of aetiological heterogeneity in Hodgkin lymphoma, discuss how may influence tumour phenotype and whether it does or impact treatment outcomes. Many new treatments are being tested era. We especially T-cell therapy immune checkpoint blockade, because these two modern expected to have differential efficacy by the presence/absence Epstein-Barr ...

Profound disruption of immune function is an established risk factor for non-Hodgkin lymphoma. We report here a large-scale evaluation of common genetic variants in immune genes and their role in lymphoma. We genotyped 57 single nucleotide polymorphisms (SNP) from 36 candidate immune genes in 1,172 non-Hodgkin lymphoma cases and 982 population-based controls from a US multicenter study. We calc...

lymphomas are solid malignant tumors having a wide spectrum of clinical and pathological features. non-hodgkin’s lymphoma (nhl) is a subtype of lymphoma with two-thirds of the cases presenting as lymph node enlargement. the remaining one third of nhl cases has been reported in the extranodal sites, including the gastro intestinal tract, waldeyer’s ring, bone, skin, and brain. intraoral non-hodg...