Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira. The whole-genome sequence of L. interrogans serovar Copenhageni together with bioinformatics tools represent a great opportunity to search for novel antigen candidates that could be used as subunit vaccine against leptospirosis. We focused on six genes encoding for conserved hypothetical proteins predicted to be exported to ...

Intracellular delivery of functional macromolecules using peptide transduction domains (PTDs) is an exciting technology with both experimental and therapeutic applications. Recent data indicate that PTD-mediated transduction occurs via fluid-phase macropinocytosis involving an intracellular pH drop to approximately 5. Nitrilotriacetic acid (NTA)-coordinated metals avidly bind hexahistidine-tagg...

This article examines corporate labor and gender relations in transatlantic perspective. It is argued that the gendered communication of IBM’s Thomas Watson, Sr. shaped labor relations in his company’s West German subsidiary. In the United States, Watson acted as a business progressive, expanding internationally, opening professional careers to young women, and implementing welfare capitalist m...

The attitude of aristocratic society to its monarch is an integral part political culture. relationship between the privileged section population and king was formed as a result activity former. article analyzes nobility three Sejmiks Ruthenian Voivodeship toward Michael I. source for this study formulas respect contained in instructions ambassadors Diet (Sejm) 1669-1673. Mentioning thanking ma...

Structures of tree topology are frequently encountered in nature and in a range of scientific domains. In this paper, a multi-step framework is presented to classify tree topologies introducing the idea of elastic matching of their sequence encodings. Initially, representative sequences of the branching topologies are obtained using node labeling and tree traversal schemes. The similarity betwe...

On some accounts, word-meanings are organized in the human-brain according to their sensory-motor attributes. We tested an alternative hypothesis: word-meanings are neuroanatomically dissociable along abstract conceptual dimensions (entities vs. events). We measured brain activity in the left middle temporal gyrus (lMTG), a brain region that has previously been shown to respond more to verbs th...

Loyalty program is a marketing effort by the merchant to keep customers loyal to their stores. It tries to keep track of the purchasing-behavior of a customer by recording customer’s purchase information, including his credit card number, as a key identifier to the customer. While it may benefit the customer, the drawback is that the privacy of the customer is intruded. If the customer is using...