glutathione (gsh) is one of the most important antioxidants that plays an essential role in detoxification of reactive oxygen species (ros) which oxidizes to glutathione disulfide (gssg). paraquat (pq), awidely used herbicide, causes pulmonary injury with the productionof ros. excessive ros accumulation as a consequence of pq exposure are frequently targeted by gsh thereby oxidative stress lead...

We present a simple and fast high-performance liquid chromatography method with fluorescence detection for the determination of the antiepileptic drug perampanel in human plasma. The chromatographic separation was performed on a Kinetex PFP (100 × 2.6 mm, 4.6 µm) column, using a mobile phase of sodium acetate 0.03 M pH 3.7 and acetonitrile (40/60, v/v), at a flow rate of 0.8 mL/min. Total chrom...

background diazinon is one of the most widely used organophosphrous pesticides in the world may affect animals and human. objectives this study was done to assess whether pseudomonas plecoglossicida can grow on diazinon as the sole carbon metabolic source in laboratory and agricultural soil. materials and methods serial dilutions of pure and commercial diazinon in minimal salt medium were made ...

The consumption of beetroot, a food rich in nitrate, has been recommended to enhance blood perfusion, restore endothelial function, and improve exercise performance. These properties may be explained by the possible effect of nitrate present in beetroot in stimulating the endogenous synthesis of nitric oxide, a potent vasodilator. However, there is limited evidence giving detailed information a...

For the first time, a novel and efficient ionic liquid-based ultrasound-assisted in-situ solvent formation microextraction (IL-UA-ISFME) combined with high-performance liquid chromatography-ultraviolet detection (HPLC-UV) has been successfully developed for the determination of duloxetine (DLX) in human plasma. Herein, an environmentally-friendly hydrophobic ionic liquid (1-butyl-3-methylimidaz...