By G. S. Robertson", Surgeon I. M. S., Officiating Civil Surgeon, Kheri. On February the 9th, at 2 p. M., a male child aged 5 days, was brought to the Sudr Dispensary. There was no anus nor any bulging in that region ; genital organs were developed ; abdomen distended and its superficial veins prominent and congested ; child very restless, and had at noon vomited faecal matter. An incision was ...

A 20-week fetus was diagnosed with tetralogy of Fallot and multicystic kidneys. The postmortem study showed missing müllerian structures with small streak ovaries, external male genitalia, and an abnormal cloacal septation (imperforate anus with a sigmoid colon opening in the bladder). As the observed anomalies were related with septation, a mechanism related with the activation of specific gro...

BACKGROUND A number of syndromes÷associations involving the caudal region have been described in the literature. Each of them is characterized by a set of morphological features. Reports on difficulties in delineation and an ever-increasing constellation of defects in recent past call for a comprehensive study into the morphologic presentations and pathogenesis of caudal embryonic defects. MA...

A 4-year-old girl with history of polydactyly and imperforate anus surgeries presented with short stature. Brain MRI revealed a large hypothalamic hamartoma (figure). Pallister-Hall syndrome (PHS) was diagnosed. Biopsy was not indicated given stable and typical tumoral appearance. Annual evaluations, hormonal replacement, and medical genetics consult were recommended. Compared to sporadic hypot...