To assess different effects of royal Jelly in protecting the human endothelial cells from high glucose level, human umbilical vein endothelial cells were exposed to various concentrations of royal jelly, from 0.625 to 10 mg/ml, at the presence of 5 and 30 mM glucose contents over a course of 72 h. In addition to cell viability assessment by conventional MTT assay, we also analyzed the feature o...

Nano-sized drugs have better distribution than their identical forms. Magnesium is the cofactor of various enzymes in lipid and glucose metabolism. In this study the effect of nano-magnesium oxide (nano-MgO) on glucose concentration and lipid profile in diabetes induced mice was evaluated in 21 laboratory mice. Mice were divided randomly into three equal groups (control, treatment and placebo)....

In this study, a sodalite nanozeolite was synthesized and characterized by X-ray diffraction (XRD) and scanning electronic microscopy (SEM). Following the morphology evolution of the sodalite nanozeolite in the SEM images illustrates the formation of the spherical particle with a size between 60 and 80 nm. Then, carbon paste electrode (CPE) was modified by sodalite nanozeolite and Ni2+ ions. Th...

Our previous report has showed that the treatment of 48 h with 22 mM glucose prevents hypoxia-induced cardiac cell death. In the present study, we investigated whether high glucose affects the mitochondrial death pathway during hypoxia, and if it does, what relates to the high glucose induced cardioprotection. Heart-derived H9c2 cells were incubated in low (5.5 mM) or high (22 mM) glucose mediu...

background and aims. a high number of patients with periodontitis may have undiagnosed diabetes. it is possible that gingival crevicular blood from routine periodontal probing may be a source of blood for glucose measurements. the aim of this study was to compare gingival crevicular blood and fingerstick blood glucose measurements using a self-monitoring device with the standard laboratory plas...

nano-sized drugs have better distribution than their identical forms. magnesium is the cofactor of various enzymes in lipid and glucose metabolism. in this study the effect of nano-magnesium oxide (nano-mgo) on glucose concentration and lipid profile in diabetes induced mice was evaluated in 21 laboratory mice. mice were divided randomly into three equal groups (control, treatment and placebo)....

diabetes is considered as a global affecting disease with an increasing contribution to both mortality rate and cost damage in the society. therefore, tight control of blood glucose levels has gained significant attention over the decades. this paper proposes a method for blood glucose level regulation in type 1 diabetics. the control strategy is based on combining the fuzzy logic theory and si...

objective (s):hyperglycemia is widely recognized as the underlying cause for some debilitating conditions in diabetic patients. the role of cannabinoid cb1 and vanilloid trpv1 receptors and their endogenous agonists, endovanilloids, in diabetic neuropathy is shown in many studies. here we have used pc12 cell line to investigate the possible influence of glucose concentration in culture medium o...

BACKGROUND/AIMS To assess the role of mitotic arrest-deficient 2-like protein 2 (MAD2B) in high glucose-induced injury in mouse glomerular endothelial cells (GEnCs). METHODS GEnCs were cultured in vitro, and MAD2B protein levels were measured by Western blot in cells stimulated with high glucose (30 mM) for various periods of time. MAD2B and scrambled shRNA were introduced into GEnCs by lipos...