نتایج جستجو برای: high dose modified release tablets
تعداد نتایج: 2662461 فیلتر نتایج به سال:
The objective of this work was to evaluate the potential use a new polymer (PAMgA) in development sustained release matrix tablets for treatment bowel inflammatory diseases. For purpose, budesonide, highly lipophilic compound, used as model drug. Tablets with two reticulation grades PAMgA (PAMgA 5 and 40) 9 mg budesonide were developed characterized. All studies carried out using biorelevant me...
Lamivudine, a BCS Class I synthetic nucleoside analogue, has a a short biological half-life of 5–7 and is mainly absorbed in the upper gastrointestinal tract. The purpose of the study is to develop a controlled release floating tablets of lamivudine employing HPMC K4M and sodium alginate. The floating tablets of lamivudine were prepared employing HPMC K4M and sodium alginate as matrix formers a...
Background and purpose: Oral route is the most frequently used route for drug administration and tablets are the most popular oral drug forms. The study of drug-excepient compatibility is an important process in development of a stable solid dosage form. Incompatibility between drugs and excipients can alter the stability and bioavailability of drugs, thereby affecting its safety and/or efficac...
Extended-release matrix tablets of diltiazem hydrochloride (DTZ) were prepared using waxy materials alone or in combination with Kollidon SR. Matrix waxy materials were carnauba wax (CW), bees wax (BW), cetyl alcohol (CA) and glyceryl monostearate (GMS). Dissolution studies were carried out by using a six stations USP XXII type 1 apparatus. The in vitro drug release study was done in 1000 ml ph...
ER is defined as a dosage form designed to release the medication in controlled manner during an extended period of time, at predetermined rate, duration, and location following administration. At steady state, rate absorption approximately equivalent elimination due metabolism excretion. (extended release) tablets shows better patient compliance through reduction frequency dose administration ...
The purpose of this investigation is to formulate and evaluate the antihypertensive drug propranolol hydrochloride sustained-release bilayer tablets. In formulation, one layer provides a loading dose through immediate release other maintenance for up 12 h controlled release. Different quantities polymers such as Kyron T-314, Hydroxypropyl methylcellulose- K4M, ethyl cellulose were used make bi-...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید