We study, in the context of object/relational mapping tools, the problem of describing mappings between inheritance hierarchies and relational schemas. To this end, we introduce a novel mapping model, called MORM+HIE , and investigate its mapping capabilities. We first show that MORM+HIE subsumes three well-know basic representation strategies for mapping a hierarchy to relations. We then show ...

Health IT is increasingly gaining significance within the IS community. This paper examines the current state of Health Information Exchange (HIE) research within the Information Systems (IS) discipline. Meta-data associated with 81 HIE articles that were published in twelve broad-based IS journals between 2000 and 2010 were examined using content analysis methodology. Using a deducto-inductive...

The use of spectrin breakdown products (SBDPs) and Tau protein levels for diagnosis and a mild hypothermia therapy for treatment of neonatal hypoxic-ischemic encephalopathy (HIE) was evaluated. One hundred and fifty infants, with HIE within 12 h after birth, participated in the study. There were 30 newborns with mild symptoms, 60 with moderate symptoms, 60 with severe symptoms, and 30 in a cont...

In this study, we attempted to design a model using Sprague-Dawley rats to better reproduce perinatal systemic hypoxic-ischemic encephalopathy (HIE) in early preterm newborns. On day 21 of gestation, the uterus of pregnant rats were exposed and the blood supply to the fetuses of neonatal HIE groups were thoroughly abscised by hemostatic clamp for 5, 10 or 15 min. Thereafter, fetuses were moved ...

OBJECTIVE The nationwide health information network (NHIN) has been proposed to securely link community and state health information exchange (HIE) entities to create a national, interoperable network for sharing healthcare data in the USA. This paper describes a framework for evaluating the costs, effort, and value of nationwide data exchange as the NHIN moves toward a production state. The pa...

Endothelial NOS (NOS3) has a potential role in the prevention of neuronal injury in hypoxic-ischemic encephalopathy (HIE). Thus, we aimed to explore the association between NOS3 gene polymorphisms and HIE susceptibility and symptoms in a Chinese Han population. Three single nucleotide polymorphisms (SNPs) in the NOS3 gene, rs1800783, rs1800779, and rs2070744, were detected in 226 children with ...

Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the important complications neonatal asphyxia, which not only leads to neurological disability but also seriously threatens life neonates. Over years, animal models HIE have been a research hotspot find ways cope with and thereby reduce risk death or in moderate-to-severe HIE. By reviewing literature related over it was found that nonhuma...

Introduction There is growing interest in leveraging available health information exchange (HIE) infrastructures to improve public health surveillance (1). The Health Information Technology for Clinical and Economic Health Act and Meaningful Use criteria for electronic health record (EHR) systems are among the factors driving the development, adoption and use of HIEs. HIEs deliver or make acces...

Haemophilus influenzae type b causes more than 95% of serious H. influenzae meningitis. H. influenzae type e (Hie) has been implicated in a few cases of meningitis. Here, we present an adult Saudi patient with Hie meningitis and review the literature. The patient, a 19-year-old Saudi male with no significant past medical history, was noted by his family to have some changes in his mentation, co...