Aim of study: To evaluate antimicrobial, immunomodulatory and hepatomodulatory effects aqueous extracts Petiveria alliacea L. (Guinea hen weed) root leaf on growing pullets.Area Abeokuta, Nigeria.Material methods: Two hundred eighty eight eight-weeks-old Isa-brown pullets were divided into treatments which consisted in birds administered or at four different concentrations (0, 15, 30 45 ɡ/L). E...

Arsenic-induced carcinogenesis can result in cancers of the liver exposed organisms. This study evaluated anticancer potentials MLF1 and AMF1 extracted from Morinda lucida Annona muicata leaves respectively Sodium arsenite (SA)-induced toxicity rats. Sixty adult female rats were randomly divided into 12 groups (n = 5). Group 1 was control. 2 received 5-weeks administrations 10 mg/kg bodyweight ...

treatment of diseases with natural remedies is gaining popularity because of its fewer side effects.   a systemic and scientific investigation of aqueous extract of euphorbia tirucalli for its antioxidant and hepatoprotective potential against carbon-tetrachloride-induced hepatic damage in rats was carried out . antioxidant property was assessed by using reducing property, superoxide anion scav...

Objective(s): Populus species have various pharmacological properties, including antioxidant activity. In this study, the effects of Populus tomentiglandulosa extract (PTE) on histopathology and antioxidant enzymes in the rat liver and kidney were examined.  Materials and Methods: Sprague-Dawley rats were assigned to three groups; (1) no...

Background: Acetaminophen (Paracetamol; PCM), commonly utilized as analgesic and antipyretic drug in many painful and febrile disorders, has been found to induce liver and renal disorders in both animals and humans. Its administration in a high dose causes hepatic and renal toxicities and results in hepato-renal cell deaths by activating multiple stress pathways. Objective: This study aimed to ...

OBJECTIVES Oxytetracycline (OTC) is a broad spectrum antibiotic widely used for treatment of a wide range of infections. However, its improper human and animal use leads to toxic effects, including hepatonephrotoxicity. Our objective was to evaluate protective effects of Nigella sativa oil (NSO) and/or ascorbic acid (AA), against OTC-induced hepatonephrotoxicity in rabbits. MATERIALS AND METH...

The present study was conducted to evaluate the effect of alcoholic extract A.webbiana leaves Lindl on liver and kidney. Wistar rats were divided into three groups (n=3) for hepatotoxicity and nephrotoxicity. Alcoholic leaves extract of A.webbiana was evaluated for protective effects against CCl4 induced hepatotoxicity and cisplatin induced nephrotoxicity. Hepatotoxicity studied by comparing pa...

Objective: To evaluate the hepato protective role of Heptoplus (HP), a ployherbal formulation as a supplementary agent for the Isoniazid and Rifampicin induced oxidative stress and apoptosis in liver. Methods: Liver cell lines were divided in to five groups. Group I is control, group II is treated with 30ng/ml of INH+RIF, group III, IV and V are supplemented with 50, 100 and 200 ng/ml of HP. At...

Article history: Received on: 02/06/2017 Accepted on: 15/07/2017 Available online: 30/09/2017 Objective: The present study aimed to evaluate the neuro-protective and hepato-protective activity of melatonin (MLN) on non-alcoholic steatohepatitis (NASH) in albino rats induced by methionine and choline deficient (MCD) diet. Material and Methods: To achieve this aim, rats were fed MCD diet for 8 we...