The enzyme alcohol dehydrogenase (ADH) is a dimeric in which each of its subunits has Zn2+ metal-containing catalytic domain and cofactor binding domain. This converts into an aldehyde. In this article, the activity was investigated by applying immobilization process directly to purified activated florisil from chicken liver. For purpose, homogenization liver achieved supernatants were separate...

In recent years the classification of glycogen storage disease has been based on the demonstration of a specific enzyme defect for each type (14). Type I, glycogenosis or von Gierke's disease, results from the lack of glucose 6-phosphatase (1). Type II, or Pompe's disease, is characterized clinically by the severity of the disease with cardiovascular complications causing death usually before t...

Non-alcoholic steatohepatitis is characterized by hepatic fat accumulation, inflammation and varying degrees of fibrosis. The dipeptidyl peptidase‑IV enzyme is important in glucose metabolism, as well as lipid accumulation, extracellular matrix metabolism and immune stimulation. Furthermore, the enzyme activity of dipeptidyl peptidase‑IV is known to be increased in non‑alcoholic steatohepatitis...

Objective(s): This study aimed to compare impacts of silver nanoparticles and silver cobalt nanoparticles on the hepatic function tests and changes in liver tissues in adult male rats.Materials and Methods: This study was conducted on 49 adult male Wistar rats, each weighing approximately 180-220 gr. The rats were randomly assigned to seven groups of seven including one control group and six ex...

Objective: This study aimed at evaluating the bioactive constituents and the toxicological profile of the aqueous fermented seed extract of P. macrophylla. Material and Methods: The chemical constituents of fermented P. macrophylla were assessed using GC-MS. For acute toxicity study, one-time doses of up to 5000 mg/kg of the extract were...