BACKGROUND AND PURPOSE Hepatocyte growth factor (HGF) is positively associated with ischemic and hemorrhagic stroke risk factors. However, understanding the relation between HGF and stroke is in its infancy. Therefore, we sought to examine the association of circulating HGF with incident stroke using data from the MESA (Multi-Ethnic Study of Atherosclerosis). We hypothesized that circulating HG...

Objective: This study was aimed to reveal the possibility of newly emerged hemorrhagic complication in acute ischemic stroke patients after the introduction of oral anticoagulants, including warfarin and direct oral anticoagulants (DOACs). Methods: Acute ischemic stroke patients who admitted to the hospital within 24 hrs following onset were consecutively screened between July 2012 and June 201...

BACKGROUND AND PURPOSE Hypertension is the most common risk factor for hemorrhagic stroke. An experimental model of stroke, the stroke-prone spontaneously hypertensive rat (SHRSP), which has been enormously useful in studies of cerebral circulation, has been used in >1000 papers. However, SHRSP usually have an ischemic or less commonly hemorrhagic stroke in the cortex, not in the brain stem, ce...

Objective: To determine the frequencies of different vascular etiologies and clinical presentations in post-partum women with suspected stroke. Study Design: Cross-sectional study. Setting: Department Medicine, Bahawal Victoria Hospital, Bahawalpur. Period: November 2022 to May 2023. Material & Methods: A total 117 female patients aged between 18-45 years period 30 days after delivery havin...

BACKGROUND AND PURPOSE Several epidemiological studies have established an association between chronic kidney disease (CKD), based on estimated glomerular filtration rate (GFR), and risk of stroke. However, sex-specific evidence for the relationship between CKD and risk of stroke and its subtypes is still limited. METHODS We conducted a prospective cohort study of 12 222 Japanese men and wome...

BACKGROUND AND PURPOSE Risk of death due to stroke in Japan is more than double the risk in the United States. It remains unknown why some ethnic groups are more prone to stroke than others. Our purpose was to compare the 20-year incidence of hospitalized stroke between Japanese-American men in the Honolulu Heart Program and white men in the Framingham Study. METHODS This was a 20-year follow...

BACKGROUND AND PURPOSE Little is known about sex-specific stroke hospitalization rates among middle-aged individuals. This study assessed recent temporal trends in stroke hospitalizations among persons aged 35 to 64 years in the United States. METHODS The Nationwide Inpatient Sample was used to identify individuals with a primary or secondary discharge diagnosis of stroke between 1997 and 200...

BACKGROUND AND PURPOSE There is ongoing controversy about the impact of hemorrhagic transformation after thrombolysis on long-term functional outcome. We sought to study the relation between the type of hemorrhagic transformation on CT scans and functional outcome. METHODS Data were obtained from the Canadian Alteplase for Stroke Effectiveness Study. This study was established as a registry t...