while a wide array of pathological changes occur in cerebral arteries following subarachnoid hemorrhage (sah), the most consistent is endothelial damage. since the endothelium normally modulates reflexes that influence vascular tone, any damage to it may represent a significant contributor to cerebral vasospasm following sah. this experimental study investigates the correlation between endothel...

there are several etiologies for agitation and headache in the recovery room, including preoperative or intraoperative drug administrations, physical disorders such as painful surgical procedures, and finally, unusual consequences of some operations such as subarachnoid hemorrhage after orbital decompression, a disastrous complication that should be particularly considered whenever facing any s...

prediction of the outcome and severity of acute upper gastrointestinal bleeding (ugib) has significant importance in patient care, disposition, and determining the need for emergent endoscopy. recent international recommendations endorse using scoring systems for management of non-variceal ugib patients. to date, different scoring systems have been developed for predicting the risk of 30-day mo...

oxygen is an essential part of the most important metabolic pathways in aerobic organisms. oxygen delivery is merely dependent on blood, rendering blood loss a devastating event. traumatic pre-hospital liver bleeding is a major cause of early trauma deaths in human and animals, with no established therapeutic method yet. increasing intra-abdominal pressure (iap) has been shown to reduce liver b...

background: magnetic resonance imaging (mri) is a safe modality and useful in characterizing normal and abnormal bone marrow (bm). mri also presents a more global view of bm than biopsy therefore, it may provide a better understanding of hematologic disorders. the purpose of this study was to monitor radiation-induced alterations of bm in acute phase of irradiation (1-10 day after total body ir...

Coronavirus disease 2019 (COVID-19) has been associated with thrombotic and endocrine complications, including adrenal insufficiency in the setting of hemorrhage. We present a patient diagnosed antiphospholipid syndrome (APLS) COVID-19 infection resulting bilateral hemorrhage, subsequently leading to insufficiency. Acute hemorrhage is an underrecognized cause decompensation, multisystem failure...

BACKGROUND AND PURPOSE Dural arteriovenous shunts with cortical venous reflux or drainage may cause neurological symptoms and death with or without intracranial hemorrhage. Present knowledge about the natural history of these lesions is limited, however. We investigated the incidences of intracranial hemorrhage, progressive dementia syndrome, and death in patients diagnosed in our neurovascular...

Objective of this study was to investigate the incidence, time, location, prevention, treatment and risk factors of recurrent hemorrhage in the earlier period of cerebral hemorrhage after operation. Three hundred and twenty two patients with operations in the earlier period of cerebral hemorrhage were analyzed retrospectively. The clinical data of hemorrhage and recurrent cerebral hemorrhage gr...

The occurrence of secondary brain stem hemorrhage was studied in 435 autopsies from patients with recent cerebral hemorrhage, infarction or ruptured cerebral aneurysms. The frequency of secondary brain stem hemorrhage was found to be 45% in cerebral hemorrhage, 15% in cerebral infarction, and 36% in ruptured aneurysms. In the majority of cases the secondary brain stem hemorrhage occurred a few ...

Background:Olanzapine is a highly tolerable and easily affordable atypical antipsychotic drug which has been commonly prescribed in both inpatient and outpatient settings for several mental disorders. Olanzapine overdose is commonly seen in psychiatric patients, who attempt suicide by intoxicating themselves with their own prescribed medications. Increased olanzapine use is associated with incr...