PURPOSE Changes in glycosylated hemoglobin (HbA(1c)) levels, blood pressure measurements, and utilization metrics among diabetic patients managed by a clinical pharmacist were studied. SUMMARY This pharmacist intervention model was developed by Polk County, Florida, to engage patients with diabetes in managing their health based on the Asheville Project's framework. The diabetes program was i...

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This study evaluated the efficacy and safety of rosiglitazone monotherapy in patients with type 2 diabetes. After a 4-week placebo run-in period, 493 patients with type 2 diabetes were randomized to receive rosiglitazone [2 or 4 mg twice daily (bd)] or placebo for 26 weeks. The primary end point was change in hemoglobin A(1c); other variables assessed included fasting plasma glucose, fructosami...

OBJECTIVE Dysglycemia is associated with poorer prognosis in patients with acute myocardial infarction (AMI). Whether admission glycemic variability (GV) has important value in prognosis of AMI patients is still unknown. The aim of the study is to investigate the prognostic value of admission GV, glucose, and glycosylated hemoglobin (HbA(1c)) in AMI patients. RESEARCH DESIGN AND METHODS We me...

Mauro Panteghini* and W. Garry John on behalf of the IFCC Scientific Division 1 Centre for Metrological Traceability in Laboratory Medicine (CIRME), University of Milan, Milan, Italy 2 Department of Clinical Sciences ‘‘Luigi Sacco’’, University of Milan, Milan, Italy 3 Clinical Biochemistry, Norfolk and Norwich University Hospital, and School of Medicine Health Policy and Practice, UEA, Norwich...

BACKGROUND In 2009, we investigated the conformance of 8 hemoglobin A(1c) (Hb A(1c)) point-of-care (POC) instruments. Since then, instruments have improved and new devices are available on the market. In this second study, we evaluated the performance of DCA Vantage, Afinion, InnovaStar, Quo-Lab, Quo-Test, Cobas B101, and B-analyst Hb A(1c) POC instruments. METHODS Clinical and Laboratory Sta...

BACKGROUND Bile acid sequestrants are a well-accepted class of cholesterol-lowering drugs. Over the last decade, small studies have indicated that these agents may also lower glucose levels in patients with type 2 diabetes mellitus (T2DM). METHODS This 26-week, randomized, double-blind, placebo-controlled, parallel-group study was conducted between August 2004 and July 2006 at 54 sites in the...

CONTEXT The impairment of insulin sensitivity, a marker of surgical stress, is important for outcomes. OBJECTIVE The aim was to assess the association between the quality of preoperative glycemic control, intraoperative insulin sensitivity, and adverse events after cardiac surgery. DESIGN AND SETTING We conducted a prospective cohort study at a tertiary care hospital. SUBJECTS Nondiabetic...

Skin intrinsic fluorescence is associated with hemoglobin A 1c and hemoglobin glycation index but not mean blood glucose in children with type 1 diabetes. In the print version of the article listed above, on page 1817, the sentence " For the second k x /k m set (set c), k x and k m were 0.5 and 0, respectively, which is useful for populations with a wide range of skin melanin (17) (further tech...