نتایج جستجو برای: hemagglutinin neuraminidase gene

تعداد نتایج: 1151308  

2011
A. AMENDOLA A. RANGHIERO A. ZANETTI E. PARIANI

Influenza viruses belong to the Orthomyxoviridae family, genus Orthomyxovirus, and are divided into three types – A, B, and C – based on the antigenic differences between their nucleoprotein and matrix proteins. Influenza A viruses are further subdivided into several subtypes. A most striking feature of influenza viruses is their ability to continually change their genetic structure – in partic...

2014
Candice Schmidt Samuel Paulo Cibulski Ana Paula Muterle Varela Camila Mengue Scheffer Adrieli Wendlant Fabiana Quoos Mayer Laura Lopes de Almeida Ana Cláudia Franco Paulo Michel Roehe

In this study, the full-genome sequence of a reassortant H1N2 swine influenza virus is reported. The isolate has the hemagglutinin (HA) and neuraminidase (NA) genes from human lineage (H1-δ cluster and N2), and the internal genes (polymerase basic 1 [PB1], polymerase basic 2 [PB2], polymerase acidic [PA], nucleoprotein [NP], matrix [M], and nonstructural [NS]) are derived from human 2009 pandem...

Journal: :The Journal of infectious diseases 2010
Glendie Marcelin Hilliary M Bland Nicholas J Negovetich Matthew R Sandbulte Ali H Ellebedy Ashley D Webb Yolanda S Griffin Jennifer L DeBeauchamp Janet E McElhaney Richard J Webby

Levels of preexisting antibodies to the hemagglutinin of pandemic influenza A(H1N1) 2009 (hereafter pandemic H1N1) virus positively correlate with age. The impact of contemporary seasonal influenza vaccines on establishing immunity to other pandemic H1N1 proteins is unknown. We measured serum antibodies to the neuraminidase (NA) of pandemic H1N1 in adults prior to and after vaccination with sea...

2017
Jose Reyes Canche-Pech Laura Conde-Ferraez Marylin Puerto-Solis Refugio Gonzalez-Losa Pilar Granja-Pérez Salha Villanueva-Jorge Maria Chan-Gasca Jesus Gómez-Carballo Luisa López-Ochoa Bertha Jiménez-Delgadillo Iram Rodríguez-Sánchez Jorge Ramírez-Prado Guadalupe Ayora-Talavera

The 2012 and 2013 annual influenza epidemics in Mexico were characterized by presenting different seasonal patterns. In 2012 the A(H1N1)pdm09 virus caused a high incidence of influenza infections after a two-year period of low circulation; whereas the 2013 epidemic presented circulation of the A(H1N1)pdm09 virus throughout the year. We have characterized the molecular composition of the Hemaggl...

2007
Ali Nazari SHIRVAN Mehran MORADI Mehdi AMINIAN Rasool MADANI

Avian influenza virus stocks (A/chicken/Iran/259/1998/(H9N2)) were propagated in the allantoic cavities of 10-day-old embryonated chicken eggs. The harvested suspension was concentrated by polyethylene glycol 6000. Concentrated samples were layered onto sucrose gradient (30%-60%). Both hemagglutinin and neuraminidase were solubilized from purified viruses with Triton X-100 across 30% sucrose gr...

2014
Chun-Hsien Tseng Hsiang-Jung Tsai Chung-Ming Chang

INTRODUCTION The following complete molecular diagnostic procedure we developed, based on real-time quantitative PCR and traditional PCR, is effective for avian influenza surveillance, virus subtyping, and viral genome sequencing. METHOD This study provides a specific and sensitive step-by-step procedure for efficient avian influenza identification of 16 hemagglutinin and 9 neuraminidase avia...

Journal: :Journal of virology 1994
T Sergel-Germano C McQuain T Morrison

Nonconservative mutations were introduced by site-specific mutagenesis into the fusion peptide and the adjacent heptad repeat region of the fusion protein of Newcastle disease virus in order to determine the role of both regions in the fusion activity of the protein. Mutations in both regions that allowed for proper folding and intracellular transport of the protein blocked the fusion activity ...

Journal: :Journal of bacteriology 1966
C De Vaux St Cyr C Howe

de Vaux St. Cyr, C. Columbia University, New York, N.Y.),and C. Howe. Immunochemical study of parainfluenza virus (type 2) in amnion cells. J. Bacteriol. 91:1911-1916. 1966.-Immunoelectrophoretic analysis of stable amnion cells in which parainfluenza virus (type 2) was being actively synthesized revealed at least three precipitating antigens not found in normal cells. These "new" antigens diffe...

Journal: :Intervirology 2015
Fahad N Almajhdi

The most comprehensive phylogenetic classification of human parainfluenza virus 3 (HPIV-3) was recently developed [PLoS One 2012;7:e43893]. This classification included three distinct clusters (A, B and C) with subdivision of cluster C into four subclusters (C1-4). In the present report, the classification of HPIV-3 was refined by inclusion of 27 overlooked beside newly characterized Saudi vari...

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