Degenerative aortic valve stenosis (AS) is the most common valvular heart disease. About two-thirds of all valve operations are for aortic valve replacement (AVR). After onset of symptoms (angina, syncope or heart failure) severe aortic stenosis has a poor prognosis with an average survival of two or three years and a high risk of sudden death. According to the ACC/AHA and the European Society ...

Described herein are five patients who had double left-sided cardiac valve replacement for mitral and aortic valve stenosis resulting from two different etiologies: rheumatic heart disease, the cause of the mitral stenosis, and congenital heart disease (bicuspid valve), the underlying cause of the aortic stenosis.

High precision is necessary during percutaneous transcatheter heart valve implantation. The precision of the implantation has been established by increasing the heart rate (usually to 200 beats per minute) to the point of significantly reduced cardiac output and thus minimizing valve movement. Routinely, this tachycardia is induced by rapid pacing. Here we report a case of failure to pace durin...

Heart murmurs are a common finding during physical examination of children but most of them are innocent or normal.recognizing the etiology of heart murmurs can help us in differential diagnosis of them.the peresent study was undertaken to determine the prevalence and etiology of heart murmurs  in 4761 school children.the sex ratio was nearly 1:1 ,murmurs were heard in 459 students (9.64%) with...

We describe a case of Gemella bergeriae endocarditis in a patient with a bicuspid aortic valve. Diagnosis was confirmed by sequencing of 16S rRNA genes in heart valve tissue. This is the first report of Gemella endocarditis confirmed by molecular detection of bacterial genes in heart valve tissue.

Prosthetic heart valves are a blessing for people with defective heart valves. One type of mechanical heart valve that was manufactured between 1979 and 1985 has been implanted in approximately 86,000 people. Between 500 and 600 of these valves are known to have failed. The failure occurs when a thin wire strut breaks free, see Figure l. The strut has two legs that are attached to the main body...

INTRODUCTION Patients with mechanical heart valve prostheses must continuously be treated with oral anticoagulants to prevent thromboembolic events related to prosthetesis. These patients should be continually evaluated for the control of oral anticoagulation. OBJECTIVE To compare the occurrence of thromboembolic and hemorragic complications in patients with mechanical heart valve prosthesis ...

Heart valve structures, derived from mesenchyme precursor cells, are composed of differentiated cell types and extracellular matrix arranged to facilitate valve function. Scleraxis (scx) is a transcription factor required for tendon cell differentiation and matrix organization. This study identified high levels of scx expression in remodeling heart valve structures at embryonic day 15.5 through...

Seven cases of single ventricle, six cases of hypoplasia of the right heart (tricuspid atresia), and one case of hypoplasia of the left heart were investigated with reflected ultrasound. In hypoplasia of the right heart there was abnormal anterior movement of the mitral valve; in hypoplasia of the left heart, abnormal anterior movement of the tricuspid valve, and in single ventricle, similiar m...

Transcatheter aortic valve implantation was developed to offer a therapeutic solution to patients with severe symptomatic aortic stenosis who are not candidates for conventional aortic valve replacement. The improvement in transcatheter aortic valve implantation outcomes is still of concern in the areas of stroke, vascular injury, heart block, paravalvular regurgitation and valve durability. Co...