The aim of this study is to investigate the frequency and clinical features of gastroesophageal reflex disease (GERD) in Parkinson's disease (PD). Consecutively recruited PD patients and controls were questioned about heartburn and GERD with a questionnaire. In PD patients, disease duration and severity, quality of life, and nonmotor symptoms were also examined and then the clinical features of...

Gastroesophageal reflux disease (GERD) occurs when acid or other stomach contents back up in the esophagus. The most common symptom of GERD is heartburn, which, while rarely life-threatening, can greatly reduce a patient’s quality of life by affecting daily activities, sleep and what they can eat [1,2]. A systematic review found the prevalence of GERD to be 1020% of the Western world with a low...

INTRODUCTION Two types of partial wrap are commonly performed in achalasia patients after Heller myotomy: the posterior 270° fundoplication (Toupet) and the anterior 180° fundoplication (Dor). The optimal type of fundoplication (posterior vs. anterior) is still debated. AIM To compare the long-term rates of dysphagia, reflux symptoms and patient satisfaction with current postoperative conditi...

Background: This study was aimed to investigate the proportion of gastroesophageal reflux (GER) among electronic cigarette (e-cig) smokers and its association with pattern e-cig smoking.Method: cross-sectional underwent community in Cirebon City, Jawa Barat, ranged from March August 2020. Subjects were enrolled through consecutive sampling method. The data collection used survey containing smok...

introduction and aims: gastroesophageal reflux disease (gerd) is very common in western countries. gerd is increasing, has profound effects on health economics, disturbs the patient's health-related quality of life, and increases the risk for development of esophageal adenocarcinoma. gerd is considered to be infrequent in developing countries. this study was performed to determine the prevalenc...

background: gastroesophageal reflux disease (gerd) is one of the most prevalent disorders affecting gastrointestinal tract with a wide range of frequency around the world. in this study, we aimed to review all of the published studies about gerd’s prevalence in iran systematically. methods: we searched bibliographic databases including pubmed and google scholar and local databases (scientific i...

OBJECTIVES/HYPOTHESIS Exposure to excess gastric acid resulting from gastroesophageal reflux disease, also known as acid reflux or heartburn, might contribute to initiation of head and neck squamous cell carcinoma, particularly laryngeal cancer. Prior epidemiologic studies have reported inconsistent results. We sought to clarify this relationship using an observational study with a larger avail...

The incidence of oesophagitis has been determined in 108 patients with sliding hiatus hernias using endoscopic, histological, and radiological criteria. Particular consideration has been given to the relationship between inflammatory disease and clinical symptoms. All the patients were attending a thoracic surgical clinic and the spectrum of disease encountered was fairly severe; over half of t...

Although proton pump inhibitors (PPI) have a record of remarkable effectiveness and safety in the management of gastroesophageal reflux disease (GERD), several treatment challenges with PPI have emerged. Dexlansoprazole MR is the (R)-enantiomer of lansoprazole contained in a formulation that produces two distinct releases of drug and significantly extends the duration of active plasma concentra...

AIM To perform a systematic review on the efficacy of intermittent and on-demand therapy with either histamine H2-receptor antagonists or proton pump inhibitors for patients with erosive oesophagitis or symptomatic heartburn. METHOD We conducted randomized-controlled trials of non-continuous therapy in gastro-oesophageal reflux disease patients. RESULTS Fourteen studies met inclusion criter...