cervical and supraclavicular lymph nodes metastases generally arise from carcinomas of the head and neck. metastases to cervical lymph nodes from the prostate are very rare. the common site for lymph node metastasis from the prostate is infradiaphrag- matic. herein, we report a 69 year-old male who presented with cervical lymph node enlargement in the setting of prostate cancer. this type of pr...

BACKGROUND Head and neck cancer constitutes a substantial portion of the burden of disease in South Asia, and there is an undersupply of surgical capacity in this region. The purpose of this study was to estimate the economic welfare losses due to head and neck cancer in India, Pakistan, and Bangladesh in 2010. METHODS We used publicly available estimates of head and neck cancer morbidity and...

Dropped head syndrome (DHS) is a famous but unusual late complication of multimodality treatment for head and neck carcinoma. We reported this early-onset complication and analyzed the dose to the neck extensor muscles. We examined the records of three patients with DHS after radiotherapy. The doses to the neck extensor muscles were compared between three patients with DHS and nine patients wit...

Locally advanced head and neck cancers are usually treated with concurrent chemoradiation. The residual nodes after chemoradiation in such patients are a common scenario, but the further investigation and treatment options in form of neck dissection are still not very clear. This review focuses on the current state of available evidence in literature for management of such patients and directs ...

Human papillomavirus (HPV) is responsible for cervical cancer, and its role in head and neck carcinoma has been reported. No drug is approved for the treatment of HPV-related diseases but cidofovir (CDV) exhibits selective antiproliferative activity. In this study, we analyzed the effects of CDV-resistance (CDVR) in two HPV(+) (SiHaCDV and HeLaCDV) and one HPV(-) (HaCaTCDV) tumor cell lines. Qu...

BACKGROUND Nedaplatin (NDP) was developed as a second-generation platinum complex. The antitumor efficacy of the combination of NDP with docetaxel (TXT) was evaluated against human head and neck carcinoma. The antitumor activity of NDP plus TXT was compared with that of some other platinum compounds, cisplatin (CDDP) and carboplatin (CBDCA) plus TXT. MATERIALS AND METHODS Mice implanted with ...

BACKGROUND Cancer is a major health-related stress and demands adequate coping. Patients with head and neck carcinoma (HNC) often face exhaustive and debilitating treatment as well as physical and functional residual effects such as disfigurement, compromised speech, dry mouth and difficulty in swallowing. Understanding how patients cope with these challenges is important in comprehensive care ...

Head and neck tumors comprise a wide spectrum of heterogeneous neoplasms for which biomarkers are needed to aid in earlier diagnosis, risk assessment and therapy response. Personalized medicine based on predictive markers linked to drug response, it is hoped, will lead to improvements in outcomes and avoidance of unnecessary treatment in carcinoma of the head and neck. Because of the heterogene...