Mesostructured titania as support for the CoMoS active phase in deep hydrodesulfurization (HDS) of 4,6-dimethydibenzothiophene (4,6-DMDBT) leads to an increase intrinsic HDS activity and a higher selectivity direct desulfurization (DDS) reaction contrast with conventional CoMoS/alumina catalyst. The temperature treatment mesostructured TiO2 support, modifies catalyst’s transformation 4,6-DMDBT....