نتایج جستجو برای: hbv surface antigen

تعداد نتایج: 816103  

Changiz Ahmadizadeh, Mina Ghodsi Garamaleki,

Background: Hepatitis B is the most common blood-borne viral infection that is considered as a major public health problem of the world's major health problems. The aim of this study was to investigate the prevalence of hepatitis B virus (HBV) infection among blood donors referring to blood transfusion centers. Methods: This retrospective cross-sectional study was performed on 216004 volunteer...

Journal: :Journal of clinical pathology 1992
J Y Lau B C Portmann G J Alexander R Williams

AIMS To determine how chronic hepatitis D virus (HDV) infection affects intrahepatic hepatitis B virus (HBV) antigen expression. METHODS Ninety eight liver biopsy specimens from 68 patients seropositive for total antibody to HDV were studied by immunohistochemistry, and the amount of HBV antigens was also quantified by radioimmunoassay in 12 patients and compared with 30 patients with chronic...

Journal: :Molecular medicine reports 2015
Meng Zhuo Linlin Song Yuyan Tang Shenglan Dai Xiaohua Chen Yongsheng Yu Guoqing Zang Zhenghao Tang

Chronic hepatitis B virus (HBV) infection is characterized by functionally impaired type 1 T-helper cell (Thl) immunity and poor HBV‑specific T‑cell responses. Ubiquitin (Ub), a highly conserved small regulatory protein, commonly serves as a signal for target proteins that are recognized and degraded in proteasomes. The rapid degradation of Ub‑mediated antigens results in efficient stimulation ...

Journal: :Fukuoka igaku zasshi = Hukuoka acta medica 2013
Hideki Ijichi Tomoharu Yoshizumi Toru Ikegami Yuji Soejima Tetsuo Ikeda Hirofumi Kawanaka Hideaki Uchiyama Yo-Ichi Yamashita Masaru Morita Eiji Oki Koshi Mimori Keishi Sugimachi Hiroshi Saeki Masayuki Watanabe Ken Shirabe Yoshihiko Maehara

Hepatitis B virus (HBV) recurrence after liver transplantation for HBV-associated liver diseases results in decreased patient and graft survival. Herein we have reported two cases of HBV recurrence following relapse of hepatocellular carcinoma (HCC) after living donor liver transplantation (LDLT). Both cases had LDLT for end-stage liver disease secondary to HBV infection with nodules of HCC exc...

Journal: :The Journal of infectious diseases 2009
Alexander Walz Stefan Wirth Jürgen Hucke Patrick Gerner

BACKGROUND Hepatitis B virus (HBV) can be transmitted by blood donors and organ donors who are positive for antibody to HBV core antigen (anti-HBc) but negative for all other HBV markers. Therefore, we evaluated the risk of infection for babies of mothers with this serostatus. METHODS A total of 2365 HBV surface antigen (HBsAg)-negative pregnant women were included in the study and screened f...

Journal: :Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 2006
Ashis Mukhopadhya Banumathi Ramakrishna Vijay Richard Rajiv Padankatti C E Eapen George M Chandy

BACKGROUND AND OBJECTIVES The relationship between hepatocyte expression of hepatitis B virus (HBV) antigens, liver histology and viral replication in asymptomatic subjects with incidental detection of hepatitis B surface antigen (HBsAg) remains unclear. We evaluated the histological activity index (HAI) and hepatocyte expression of viral antigens with replicative status in asymptomatic chronic...

Journal: :Enfermedades infecciosas y microbiologia clinica 2008
Francisco Rodríguez-Frias Rosendo Jardi

The hepatitis B virus (HBV) belongs to the hepadnavirus family. The genome of the virus, formed by a small DNA molecule with 3,200 base pairs, has 4 strongly overlapping protein coding regions: ORF preS/S, corresponding to the envelope proteins that constitute the HBV surface antigen (HBsAg); ORF preC/C, which encodes the viral capsid component (core antigen or HBcAg) and a non-structural prote...

2017
Lei Wang Min Cao Qing Lu Wei Zhong Hua Zhao Qin Xiang Hui Juan Wang Hua Tang Zhang Guo Qi Lai

Despite the availability of an effective vaccine, hepatitis B virus (HBV) infection remains a major health problem. HBV e antigen (HBeAg)-negative strains have become prevalent. Previously, no animal model mimicked the clinical course of HBeAg-negative HBV infection. To establish an HBeAg-negative HBV infection model, the 3.2-kb full-length genome of HBeAg-negative HBV was cloned from a clinica...

2016
Berthold Bivigou-Mboumba Sandrine François-Souquière Luc Deleplancque Jeanne Sica Augustin Mouinga-Ondémé Marie Amougou-Atsama Marie-Laure Chaix Richard Njouom François Rouet Pierre Roques

Integrated data on hepatitis B virus (HBV) patterns, HBV genotypes and mutations are lacking in human immunodeficiency virus type 1 (HIV-1) co-infected patients from Africa. This survey was conducted in 2010-2013 among 762 HIV-1-positive adults from Gabon who were predominantly treated with 3TC-based antiretroviral treatment. HBV patterns were identified using immunoassays detecting total antib...

Journal: :iranian journal of pathology 2009
arezoo aghakhani amitis ramezani minoo mohraz mohammad banifazl ali eslamifar

background and objective: presence of hepatitis b core antibody (anti-hbc) in the absence of hepatitis b surface antigen (hbsag) and hepatitis b surface antibody (anti-hbs) is defined, as isolated anti-hbc. little is known about the clinical significance of the isolated anti-hbc in hepatitis b virus (hbv) infections. the aim of this study was to assess the significance of anti-hbc as the only m...

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