We take the view (advanced, among others, by Schumpeter) that new ideas are original combinations of existing elements. While many random combinations are useless, some represent combinations which ”...t” together, aggregating di¤erent components in a novel and functional way. Thus, in order to appraise an innovative idea it is necessary to have specialized experts examine whether each of its d...

Prion protein (PrP) is critically involved in the transmission and pathogenesis of the transmissible spongiform encephalopathies (TSEs), which include scrapie in sheep, variant and sporadic Creutzfeldt–Jakob disease (CJD) in humans and bovine spongiform encephalopathy (BSE) in cattle. The normal, cellular PrPc protein encoded by the Prnp gene is required for susceptibility to TSE. The interconv...

Software product lines continue to provide adopters with gains in many areas such as faster time to market and increased productivity. The recent Software Product Line Conference (SPLC) provided a forum in which a spectrum of results were reported. In this issue of Strategic Software Engineering I will use the activities at SPLC to focus on a couple of interesting areas that have strategic impo...

9s. 6d.) London: Mills & Boom, 19,64. THIS well produced book has an informal and friendly approach and is designed especially for girls who will soon leave school. It starts with the family in the home and considers personal hygiene, the house, heating and ventilation, water supplies and sanitary services. It has three well-informed and balanced chapters on food, on food poisoning and on the h...

The question of the relationship between ideas and realisations is an old one and a still ongoing discussion in (legal) philosophy and theory. The use of some results can support present endeavours concerning the building of legal ontologies. Kelsen’s pure theory of law is the basis for our comprehensive legal ontology. Other improvements are the integration of visualisations and relations betw...

The study of human categorization is contentious because it matters. How we understand the processes that give rise to categories is at the very core of how we understand human cognition. Over the past several decades, there has been growing concern that the assumptions that define and distinguish competing theories may notbe quite right. These assumptions are based on the traditional metaphor ...

There will also be all-weather Bio-Domes designed by Jerry Tate (architect of the CORE educational facilities at the Eden Project). Feeling peckish? Enjoy a feast on the Slow Food Moving Restaurant, where tables and chairs snake up through the ‘hanging gardens’ atrium, into rooms created by food-artists. Discover innovative, fresh, locally produced food, designed to stimulate all the senses, de...