Introduction Stigma in mental health settings is described as a set of negative and unrealistic beliefs about those with illness. Authors suggest that stigma consistently underdefined overused, leading to resources toward preventing managing this problem lacking intention efficiency. Three interacting levels are defined: social, structural, internalized or self-stigma. Internalized refers how p...

OBJECTIVE Programme implementers have argued that the increasing availability of antiretroviral therapy (ART) will reduce the stigma of HIV. We analyzed data from Uganda to assess how HIV-related stigma has changed during a period of ART expansion. DESIGN Serial cross-sectional surveys. METHODS We analyzed data from the Uganda AIDS Rural Treatment Outcomes study during 2007-2012 to estimate...

The model minority myth (MMM) has far-reaching implications for Asian Americans in many settings, including medicine. For clinicians working with first-generation American college students, this article considers 3 factors that affect how the MMM plays out clinical care: clinicians' racial identity awareness, cross-racial dynamics, and extent to which a patient internalized racism or oppression.

Direct experimental proof has been sought for the hypothesis that liposomal drugs targeted against internalizing epitopes (e.g., CD19) will have higher therapeutic efficacies than those targeted against noninternalizing epitopes (e.g., CD20). Anti-CD19-targeted liposomes were rapidly internalized into human B-lymphoma (Namalwa) cells, whereas those targeted with anti-CD20 were not internalized....

Clathrin-mediated endocytosis (CME) is the major pathway of epidermal growth factor receptor (EGFR) internalization. It is commonly believed that CME mediates long-term attenuation of EGFR signaling by targeting the receptor for degradation. However, the EGFR can also be internalized through (a) clathrin-independent pathway(s), and it remains unclear why distinct mechanisms of internalization h...

The purpose of this exploratory study was to cross-culturally examine associations among self-construals, comparative vs. internalized self-criticisms, self-compassion, and depressive symptoms. 1200 undergraduates in the city of Kyoto, Japan, and 420 college students in Tennessee and Michigan participated in this study. The results indicated that both independent and interdependent self-constru...

Reveromycin A (Rev.A) is an inhibitor of epidermal growth factor-dependent cell growth that is produced from the culture broth of an actinomycete strain. Rev.A was assessed for its ability to regulate antigen (Ag) presentation by A20-HL B lymphoma cells bearing trinitrophenyl (TNP)-specific surface IgM (sIgM) to cloned T cells specific for OVA(323-339)/I-Ad. Rev.A-treatment inhibited the presen...

The Gram-negative bacterium Campylobacter jejuni is able to enter, survive and multiply within the free living amoeba Acanthamoeba polyphaga, but the molecular mechanisms behind these events are still unclear. We have studied the uptake and intracellular trafficking of viable and heat killed bacterial cells of the C. jejuni strain 81-176 in A. polyphaga. We found that viable bacteria associated...

Experiences with weight stigma negatively impact both psychological outcomes (e.g., body dissatisfaction, depression) and behavioral outcomes (e.g., dieting, exercise). However, not everyone is equally affected by experiences with weight stigma. This study examined whether internalized societal attitudes about weight moderated the impact of weight stigma. Adult participants (n = 111) completed ...