نتایج جستجو برای: harvard g5
تعداد نتایج: 14660 فیلتر نتایج به سال:
The aim of the present study was to investigate the therapeutic potential of a double suicide gene, thymidine kinase (TK) combined with cytosine deaminase (CD), mediated by generation of 5-polyamidoamine dendrimers (G5-PAMAM-D) on human Tenon's capsule fibroblasts (HTFs) as an anti-scarring agent. The pAcGFP1-Hyg-TK-CD plasmid was transfected into HTFs, and reverse-transcription polymerase chai...
We report a facile approach to forming dendrimer-stabilized gold nanoparticles (Au DSNPs) through the use of amine-terminated fifth-generation poly(amidoamine) (PAMAM) dendrimers modified by diatrizoic acid (G5.NH(2)-DTA) as stabilizers for enhanced computed tomography (CT) imaging applications. In this study, by simply mixing G5.NH(2)-DTA dendrimers with gold salt in aqueous solution at room t...
The consumption of fatty acids, nutrients, and regular physical activity, individually influence bone mechanical properties in rats. To investigate their effects in combination, male rats were divided into the seven groups: G1: regular food and drinking water; G2: same as Gr.1 + physical activity (Whole body vibration; WBV); G3: same as Gr.2 + Calcium, Vit. D, Boron; G4: same as Gr.3 + canola o...
In this article, the disclinated modifications of two-dimensional phosphorene crystals are modelled. The modelling technique explores crystal lattices graphenes known as pseudo-graphenes to form a family materials sharing same lattice structure and symmetry. To design phosphorenes Ph5-7v1 Ph5‑6‑7v2, structures G5-7v1 G5‑6‑7v2 chosen reference ones, respectively. Optimization procedure done with...
ABS TRACT Objective: In our study, we investigated transient receptor potential melastatin 7 (TRPM7) immunoreactivity in pre- and posttreatment pathology samples of patients with endometrial hyperplasia (EH) who responded to progesterone therapy were resistant therapy. Material Methods: this retrospective, comparative single-center case-control tissue TRPM7 was evaluated sections obtained from ...
Background: Studies focus on the incidence and risk factors (RFs) associated with reaching final stage of chronic kidney disease (CKD-G5) receiving replacement therapy (KRT). Analysis those related to CKD-G5 while conservative management (CKM) has been neglected. Methods: Retrospective cohort study analysing electronic health records individuals aged ≥ 50 eGFR < 60 mL/min/m2. Cumulative rate...
The c-Myc (Myc) oncoprotein is a high-value therapeutic target given that it is deregulated in multiple types of cancer. However, potent small molecule inhibitors of Myc have been difficult to identify, particularly those whose mechanism relies on blocking the association between Myc and its obligate heterodimerization partner, Max. We have recently reported a structure-activity relationship st...
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