Composites of hydroxyapatite (HAp) are widely employed in biomedical applications due to their biocompatibility, bioactivity and osteoconductivity properties. In fact, the development of industrially scalable hybrids at low cost and high efficiency has a great impact, for example, on bone tissue engineering applications and even as drug delivery systems. New nanocomposites constituted by HAp na...

Abstract Herein, we analyzed the morphology of atmospheric plasma-sprayed (APS) coating on medical 316L stainless steel and its influence physical electrochemical properties implant application. Five types coatings were examined: hydroxyapatite (HAp), titanium (Ti), zirconium (Zr), Ti/HAp Zr/HAp. The base via chemical phase composition, surface topography, wettability in particular corrosion re...

Hydroxyapatite (HAP) is the major inorganic component of bones and teeth. The characterization of HAP surfaces on the molecular level is important for achieving a fundamental understanding of bone remodeling and dental caries processes. On the microscopic level, hydroxyapatite growth and dissolution reactions mainly occur at steps. Therefore, this study focuses on individual molecular steps on ...

High-energy synchrotron X-ray diffraction is used to study in situ elastic strains in hydroxyapatite (HAP) for bovine femur cortical bone subjected to uniaxial compressive loading. Load-unload tests at room temperature (27°C) and body temperature (37°C) show that the load transfer to the stiff nanosized HAP platelets from the surrounding compliant protein matrix does not vary significantly (p<0...

We have measured the interaction forces between a murine melanoma cell and a poly(l-lactic acid) (PLLA) microsphere coated with/without hydroxyapatite (HAp) nanoparticles (i.e., an HAp/PLLA or a bare PLLA microsphere) in a serum-free culture medium, using atomic force microscopy (AFM) with colloid probe technique, in order to investigate how the HAp-nanoparticle coating as well as interfacial s...

Bioactivity and biocompatibility are crucial for tissue engineering scaffolds. In this study, hydroxyapatite (HAP) was incorporated into polyetheretherketone/polyglycolicacid (PEEK/PGA) hybrid to improve its biological properties, and the composite scaffolds were developed via selective laser sintering (SLS). The effects of HAP on physical and chemical properties of the composite scaffolds were...

Hospital-acquired pneumonia (HAP) is one of the most common causes of nosocomial infection, morbidity, and mortality in hospitalized patients. Many patient- and disease-specific factors contribute to the pathophysiology of HAP, particularly in the surgical population. Risk-factor modification and inpatient prevention strategies can have a significant impact on the incidence of HAP. While the be...

Dicalcium phosphate dihydrate (DCPD) reacts with fluoride ion in an aqueous solution and forms stable fluoroapatite (FAp). This reaction requires a lag time to form nano-sized precursor, hydroxyapatite (HAp)-like calcium phosphate, on DCPD surface. This long lag time prevents DCPD from applying as an effective fluoride removal agent from waste water. The purpose of this study is to improve the ...