نتایج جستجو برای: halogen compounds

تعداد نتایج: 230653  

1995
Mika Pettersson Jan Lundell Markku Räsänen

Ultraviolet-irradiation of hydrogen halide containing rare gas matrices yields the formation of linear centrosymmetric cations of type ~XHX!, ~X5Ar, Kr, Xe!. Annealing of the irradiated doped solids produces, along with thermoluminescence, extremely strong absorptions in the 1700–1000 cm region. Based on isotopic substitution and halogen dependence of these bands, the presence of hydrogen and h...

2001
Chris D Geddes

In the last century the production and application of halides assumed an ever greater importance. In the fields of medicine, dentistry, plastics, pesticides, food, photography etc many new halogen containing compounds have come into everyday use. In an analogous manner many techniques for the detection and determination of halogen compounds and ions have been developed with scientific journals ...

Journal: :Cancer research 1968
L W Wattenberg M A Page J L Leong

SUMMARY A study of the relationships between structure of 2-phenylbenzothiazoles and related compounds and their ca pacity to induce increased benzpyrene hydroxylase activity in the liver and lung of the rat has been carried out. Thirty-three compounds have been studied. It has been found that intro duction of an appropriate halogen into the 4'-phenyl position approximately doubles inducing act...

Journal: :The Biochemical journal 1964
P L Grover P Sims

Booth, Boyland & Sims (1961) described and partially purified an enzyme from the soluble supernatant of rat liver which catalyses conjugations of glutathione with aromatic compounds to form thio ethers as a first stage in mercapturic acid biosynthesis, and an apparently similar enzyme has been shown to be involved in processes leading to the biliary excretion of sulphobromophthalein (phenoltetr...

Journal: :Toxicology letters 2000
A S Christophersen

The methylenedioxy-derivatives of amphetamine and methamphetamine represent the largest group of designer drugs. The most frequently used compounds are 3,4-methylenedioxy-methamphetamine (MDMA-ecstasy) and 3,4-methylenedioxy-amphetamine (MDA), first synthesised in 1910 (MDA) and 1914 (MDMA), respectively, to be used as an appetite suppressant. At the end of the 1960s, non-medical (recreational)...

2016
Sreekanth Kokkonda Xiaoyi Deng Karen L. White Jose M. Coteron Maria Marco Laura de las Heras John White Farah El Mazouni Diana R. Tomchick Krishne Manjalanagara Kakali Rani Rudra Gong Chen Julia Morizzi Eileen Ryan Werner Kaminsky Didier Leroy María Santos Martínez-Martínez Maria Belen Jimenez-Diaz Santiago Ferrer Bazaga Iñigo Angulo-Barturen David Waterson Jeremy N. Burrows Dave Matthews Susan A. Charman Margaret A. Phillips Pradipsinh K. Rathod

Malaria persists as one of the most devastating global infectious diseases. The pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase (DHODH) has been identified as a new malaria drug target, and a triazolopyrimidine-based DHODH inhibitor 1 (DSM265) is in clinical development. We sought to identify compounds with higher potency against Plasmodium DHODH while showing greater selectivity to...

2013
Arri Priimagi Gabriella Cavallo Pierangelo Metrangolo Giuseppe Resnati

Halogen bonding is an emerging noncovalent interaction for constructing supramolecular assemblies. Though similar to the more familiar hydrogen bonding, four primary differences between these two interactions make halogen bonding a unique tool for molecular recognition and the design of functional materials. First, halogen bonds tend to be much more directional than (single) hydrogen bonds. Sec...

2014
Pierangelo Metrangolo Giuseppe Resnati

Cl/Br/I alternative substitutions in a series of dihalophenols indicate that type I and type II halogen···halogen contacts have different chemical nature. Only the latter ones qualify as true halogen bonds, according to the recent IUPAC definition.

2016
J. Fuger

— The present status of our information on the thermodynamics of the actinide halogeno-complexes with alkali metal ions is reviewed, with special emphasis on chloroand bromo-derivatives. Where enough thermodynamic and structural data are available, attempts are made to deduce the evolution of the energetics of the actinide-halogen bonds along a series of isomorphous or analogous compounds. The ...

Journal: :Antimicrobial agents and chemotherapy 1990
C Conti D Genovese R Santoro M L Stein N Orsi L Fiore

The effects of some halogen-substituted flavanoids (dichloroflavan, halogenated isoflavans, and isoflavenes) on poliovirus type 2 infection was examined. Only two isoflavenes exhibited a significant inhibitory activity on the virus-induced cytopathic effect and plaque formation. In a single cycle of viral replication, both compounds reduced the viral yield by approximately 90%. The presence of ...

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