نتایج جستجو برای: h9n2 avian influenza

تعداد نتایج: 103101  

Journal: :Journal of virology 2012
Suhong Zhao Langsizhu Suo Meilin Jin

In this report, a novel H5N2 avian influenza virus (AIV) was isolated from chickens in Tibet in 2010, western China. Phylogenetic analysis demonstrated that it was a natural reassortant between H9N2 and H5N1 subtypes. It is of note that this virus has an HP genotype with HA, PB2, M, and NS genes homologous to those of A/peregrine falcon/Hong Kong/2142/2008(H5N1)-like HPAIV isolated from dead wi...

2015
Ningning Sun Wanchun Sun Shuiming Li Jingbo Yang Longfei Yang Guihua Quan Xiang Gao Zijian Wang Xin Cheng Zehui Li Qisheng Peng Ning Liu David Sheehan

Avian influenza A viruses are serious veterinary pathogens that normally circulate among avian populations, causing substantial economic impacts. Some strains of avian influenza A viruses, such as H5N1, H9N2, and recently reported H7N9, have been occasionally found to adapt to humans from other species. In order to replicate efficiently in the new host, influenza viruses have to interact with a...

Journal: :iranian journal of virology 0
zohreh mojahedi razi vaccine and serum research institute, alborz, iran mahdi vasfi marandi faculty of veterinary medicine, tehran university, tehran, iran khosrow aghaipour razi vaccine and serum research institute, alborz, iran hamid mahdavi polyemer and petrochemical institute, tehran, iran seyed ali pourbakhsh razi vaccine and serum research institute, alborz, iran ali anissian department of veterinary medicine, islamic azad university, abhar, iran

abstract background and aims: vaccination of poultry has a major impact on the prevention and control of avian influenza viruses. nanobiotechnology techniques provide a new approach for improvement of influenza vaccine efficacy. in this study, efficacy of an inactivated nano-adjuvant vaccine developed based on an endemic h9n2 virus was evaluated in spf chickens. materials and methods: in each t...

2017
Xiaoli Hao Jiongjiong Wang Jiao Hu Xiaolong Lu Zhao Gao Dong Liu Juan Li Xiaoquan Wang Min Gu Zenglei Hu Xiaowen Liu Shunlin Hu Xiulong Xu Daxin Peng Xinan Jiao Xiufan Liu

H9N2 avian influenza virus (AIV) of genotype S frequently donate internal genes to facilitate the generation of novel reassortants such as H7N9, H10N8, H5N2 and H5N6 AIVs, posing an enormous threat to both human health and poultry industry. However, the pathogenicity and transmission of reassortant H5 viruses with internal gene cassette of genotype S H9N2-origin in chickens and mice remain unkn...

2016
Hao Zhou Shun Chen Bing Yan Hongjun Chen Mingshu Wang Renyong Jia Dekang Zhu Mafeng Liu Fei Liu Qiao Yang Ying Wu Kunfeng Sun Xiaoyue Chen Bo Jing Anchun Cheng

Geese, as aquatic birds, are an important natural reservoir of avian influenza virus (AIV). To characterize the innate antiviral immune response against AIV H9N2 strain infection in geese as well as the probable relationship between the expression of immune-related genes and the distribution of viral antigens, we investigated the levels of immune-related gene transcription both in AIV H9N2 stra...

2013
Anna H. Y. Law Alex H. M. Tam Davy C. W. Lee Allan S. Y. Lau

Influenza viruses of avian origin continue to pose pandemic threats to human health. Some of the H5N1 and H9N2 virus subtypes induce markedly elevated cytokine levels when compared with the seasonal H1N1 virus. We previously showed that H5N1/97 hyperinduces tumor necrosis factor (TNF)-alpha through p38 mitogen activated protein kinase (MAPK). However, the detailed mechanisms of p38MAPK activati...

2012
Xiaokang Li Wenbao Qi Jun He Zhangyong Ning Yue Hu Jin Tian Peirong Jiao Chenggang Xu Jianxin Chen Juergen Richt Wenjun Ma Ming Liao

H9N2 subtype avian influenza viruses (AIVs) have shown expanded host range and can infect mammals, such as humans and swine. To date the mechanisms of mammalian adaptation and interspecies transmission of H9N2 AIVs remain poorly understood. To explore the molecular basis determining mammalian adaptation of H9N2 AIVs, we compared two avian field H9N2 isolates in a mouse model: one (A/chicken/Gua...

2016
Jun Chu Qiang Zhang Tianyuan Zhang Er Han Peng Zhao Ahrar Khan Cheng He Yongzheng Wu

Avian influenza virus subtype H9N2 (H9N2) and Chlamydia psittaci (C. psittaci) are frequently isolated in chickens with respiratory disease. However, their roles in co-infection remain unclear. We tested the hypothesis that C. psittaci enhances H9N2 infection through suppression of host immunity. Thus, 10-day-old SPF chickens were inoculated intra-tracheally with a high or low virulence C. psit...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Mikhail N Matrosovich Tatyana Y Matrosovich Thomas Gray Noel A Roberts Hans-Dieter Klenk

The recent human infections caused by H5N1, H9N2, and H7N7 avian influenza viruses highlighted the continuous threat of new pathogenic influenza viruses emerging from a natural reservoir in birds. It is generally believed that replication of avian influenza viruses in humans is restricted by a poor fit of these viruses to cellular receptors and extracellular inhibitors in the human respiratory ...

2014
Changwen Ke Jing Lu Jie Wu Dawei Guan Lirong Zou Tie Song Lina Yi Xianqiao Zeng Lijun Liang Hanzhong Ni Min Kang Xin Zhang Haojie Zhong Jianfeng He Jinyan Lin Derek Smith David Burke Ron A.M. Fouchier Marion Koopmans Yonghui Zhang

Influenza A(H7N9) virus emerged in eastern China in February 2013 and continues to circulate in this region, but its ecology is poorly understood. In April 2013, the Guangdong Provincial Center for Disease Control and Prevention (CDC) implemented environmental and human syndromic surveillance for the virus. Environmental samples from poultry markets in 21 city CDCs (n=8,942) and respiratory sam...

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