The disease spectrum associated with human bocavirus-1 infection remains to be fully defined. We report a case of bocavirus-1-associated bronchiolitis, leading to severe respiratory failure and extracorporeal membrane oxygenation in a 4-year-old child, and suggest blood testing for human bocavirus-1 in children with severe respiratory tract infection.

In a recent issue of Critical Care, we read with great interest the article by Enger and colleagues [1] regarding the development of novel mortality prediction models on extracorporeal membrane oxygenation (ECMO) in acute respiratory failure and the comparison of its performance with the ECMOnet (Extracorporeal Membrane Oxygenation Network) [2], PRESERVE (Predicting Death for Severe Acute Respi...

A 24-year-old pregnant woman (29.4 weeks of gestation) with A (H1N1) influenza-associated adult respiratory distress syndrome was admitted to the intensive care unit. The patient was connected to femoral-jugular veno-venous extracorporeal membrane oxygenation (ECMO) 8 hours after admission. On the 7(th) day of ECMO support, due to the increasing threat to the life of the mother and the fetus, a...

BACKGROUND In patients with A(H1N1)pdm09 infection, severe lung involvement requiring admission to intensive care units (ICU) has been reported. Mutations at the hemagglutinin (HA) receptor binding site (RBS) have been associated with increased virulence and disease severity, representing a potential marker of critical illness. OBJECTIVES To assess the contribution of HA-RBS variability in cr...

Dear Editor, a new H1N1 pandemic flu is approaching Europe. In Italy, the results obtained from the “ECMOnet” network, for the centralization of patients with adult respiratory distress syndrome (ARDS) in structures with extracorporeal membrane oxygenation (ECMO) support, are encouraging (1,2) but far from being exhaustive, mainly because of the small number of patients treated. The ECMO techni...

Various types of extracorporeal membrane oxygenation methods have been used in liver transplant operations. The main indications are portopulmonary or hepatopulmonary syndromes and other cardiorespiratory failure syndromes that are refractory to conventional therapy. There is little literature available about extracorporeal membrane oxygenation, especially after liver transplant. We describe ou...

A previously well 20-year-old man with a history of nasal inhalation of "speed" was retrieved on extracorporeal membrane oxygenation for respiratory failure. Anti-glomerular basement membrane (anti-GBM) antibody was positive in the absence of renal disease. We postulate a hitherto unreported causal link between snorting "speed" and lung disease associated with anti-GBM antibody formation.

Obstetric patients have risk factors for severe COVID-19 disease, including obesity, hypertension, and diabetes [1]. Pregnant are more likely to be hospitalized, admitted the intensive care unit (ICU), experience acute respiratory distress syndrome (ARDS), require invasive ventilation extracorporeal membrane oxygenation (ECMO) [1,2]. The use of ECMO in pregnant with COVID-19-associated failure ...