Hypericin is a pigment present in the widely distributed medicinal plant Hypericum perforatum L. (Hypericaceae). In our research, hypericin was found to be an inhibitor of NADPH/Fe 2+ induced microsomal lipid peroxidation and NADPH-dependent lucigenin chemiluminescence emission in vitro. Hypericin also inhibited the microsomal CYP1Adependent 7-ethoxyresorufin O-deethylase (EROD) which participa...

Hypericin, extracted from H. perforatum, can induce the generation of reactive oxygen species by visible light irradiation, which may consequently induce the conformational change of hemoglobin. We have not only employed UV-vis spectroscopy to observe the changes of UV-vis spectra of the protein, which reveals the conformational changes of the protein, but also employed electrochemical method t...

The process extraction of hypericin from the aerial parts Hypericum scabrum and perforatum was studied. On basis results research, following conditions were established: extractant – 80% ethanol, particle size raw material no more than 8 mm temperature 20–40 °C. By method mathematical planning experiment according to Box-Wilson, determined, which ensure with a yield 95%. Proposed five-fold H. n...

Alternative oxidase (AOX) protein is located in the inner mitochondrial membrane and is encoded in the nuclear genome being involved in plant response upon a diversity of environmental stresses and also in normal plant growth and development. Here we report the characterization of the AOX gene family of Hypericum perforatum L. Two AOX genes were identified, both with a structure of four exons (...

Fungal elicitor prepared from the cell walls of Aspergillum niger induces multiple responses of Hypericum perforatum cells, including nitric oxide (NO) generation, jasmonic acid (JA) biosynthesis, and hypericin production. To determine the role of NO and JA in elicitor-induced hypericin production, we study the effects of NO scavenger 2- to 4-carboxyphenyl-4,4, 5,5-tetramethylimidazoline-1-oxyl...

Muğla İli Ula İlçesi Merkez ve bağlı mahallelerinde 2016-2018 yılları arasında yaptığımız etnobotanik alan çalışmamızda farklı yaş sosyal kategorilerden kişilerle görüşülmüştür. Çalışma alanımız olan Ula’da 53 familyaya ait 123 bitki türü kaydedilmiştir. Bu bitkilerden 70 tanesi yörede doğal yayılışa sahip olup,45 de halk tarafından yetiştirilmektedir.10 ise hiçbir şekilde yetiştirilmemektedir....