Oxidative stress and genotoxicity induced by intraperitoneally implanted polycaprolactone (PCL) were evaluated in present study. In an effort to assess oxidative stress induced liver injury, we measured hematological indices, biochemical parameters of liver function and levels of oxidative stress biomarkers such as lipid peroxidation (LPO), 8hydroxy-2’deoxy guanosine (8-OHdG), reduced glutathio...

The objective of the present study was to determine the frequency of somatic chromosomal anomalies and Y chromosomal microdeletions (azoospermia factor genes, AZF) in infertile males who seek assisted reproduction. These studies are very important because the assisted reproduction techniques (mainly intracytoplasmic sperm injection) bypass the natural selection process and some classical chromo...

Objective: To investigate antenatal detection the chromosome abnormalities in high risk pregnancies and correlation between karyotype analysis and FISH (Fluorescent In Situ Hybridization). Method: Were analyzed cytogenetic results from a total of 594 cases between 2008-2009. Amniotic fluid karyotyping and FISH have been offered to pregnant women with genetic risk, using the standard method and ...

INTRODUCTION Infertility is a significant multifactorial disorder that can be caused by chromosomal abnormalities. In this study, we aimed to cytogenetically investigate male and female patients admitted to the Genetic Diagnostic Laboratory of Kayseri Educational Hospital in Kayseri, Turkey with varied clinical prediagnoses of infertility. MATERIALS AND METHODS Chromosomes from cultured perip...

Within cytogenetic preparations chromosomal breaks can be observed in patients suffering from Fanconi anemia (FA), a recessively inherited syndrome with an extremely elevated cancer risk, but also in healthy individuals as so-called fragile sites (FS). It is known that FS cytogenetically co-localize with tumorand evolutionaryconserved chromosomal break-points. The also suggested colocalization ...

Recently fluorescence in situ hybridization protocols have been developed which allow the painting of individual chromosomes using DNA-libraries from sorted human chromosomes. This approach has the particular advantage that radiation induced chromosome translocations can be easily detected, if chromosomes of distinctly different colors take part in the translocation event. To enhance the sensit...

We propose a coloring algorithm for sparse random graphs generated by the geographical threshold graph (GTG) model, a generalization of random geometric graphs (RGG). In a GTG, nodes are distributed in a Euclidean space, and edges are assigned according to a threshold function involving the distance between nodes as well as randomly chosen node weights. The motivation for analyzing this model i...

The chromosomal banding properties of Oxynoemacheilus simavicus (Balık & Bănărescu, 1978) were revealed out by C-banding and silver staining. Constitutive heterochromatin regions determined on the pericentromeres most chromosomes C-banding. Otherwise, nucleolus organizer (NORs) observed short (p) arms one middle-sized submetacentric (sm) chromosome pair Also, Ag-NOR size number polymorphism...