OBJECTIVE The aim of this study was to develop birth weight references for twins. Mean birth weights of individual twins are lower than those of singletons, hence singleton birth weight curves may not be suitable to assess twin birth weights. STUDY DESIGN Twin birth weight curves were developed according to gestational age, gender, parity and mode of -conception. The curves are based on popul...

Reference percentile curves represent the covariate-dependent distribution of a quantitative measurement and are often used to summarize and monitor dynamic processes such as human growth. We propose a new nonparametric method based on a radial smoothing (RS) technique to estimate age-specific reference percentile curves assuming the underlying distribution is relatively close to normal. We com...

Objective: To verify the applicability of standard fetal growth curves proposed for western populations to an Indian population. Method: Thirty patients were included and ultrasound scans were performed on Indian pregnant women to measure fetal growth parameters of biparietal diameter, head circumference, abdominal circumference and femur length for every weekly interval from 14 to 40 weeks. Tw...

This report discusses the cross-section shapes and growth curves created by different proliferation algorithms in an in silico model of in vitro multicellular tumor spheroid growth (MTS). The in vitro MTS system is a model of in vivo tumor growth. The in silico model described herein represents aspects of MTS growth, including its layered structure and growth patterns. An exploration of four al...

Understanding the patterns of genetic variation and constraint for continuous reaction norms, growth trajectories, and other function-valued traits is challenging. We describe and illustrate a recent analytical method, simple basis analysis (SBA), that uses the genetic variance-covariance (G) matrix to identify "simple" directions of genetic variation and genetic constraints that have straightf...