It is now well documented that ageing is associated with brain shrinkage, particularly in late adulthood [1,2]. From age 60 onwards, the average adult brain atrophies 0.5%/yr for the whole brain, 0.33%/yr for grey matter and 0.62–0.68%/yr for white matter [3–5]. This may seem small, but cumulatively adds up to substantial volume losses over decades: between the ages of 60 and 70, approximately ...

Handedness is thought to originate in the brain, but identifying its structural correlates in the cortex has yielded surprisingly incoherent results. One idea proclaimed by several authors is that structural grey matter asymmetries might underlie handedness. While some authors have found significant associations with handedness in different brain areas (e.g. in the central sulcus and precentral...

the aim of this paper is to develop a prediction model of energy demand of iran’s industrial sector. for that matter a markov chain grey model (mcgm) has been proposed to forecast such energy demand. to find the effectiveness of the proposed model, it is then compared with grey model (gm) and regression model. the comparison reveals that the mcgm model has higher precision than those of the gm ...

Current clinical practice in the premature infant with posthaemorrhagic ventricular dilatation (PHVD) includes drainage of cerebrospinal fluid (CSF). This case study used advanced volumetric three dimensional magnetic resonance imaging to document the impact of CSF removal on the volume of regional brain tissues in a premature infant with PHVD. The removal of a large volume of CSF was associate...

BACKGROUND/AIMS Alleles of the FMR1 gene containing small expansions of the CGG-trinucleotide repeat comprise premutation and grey-zone alleles. Premutation alleles may cause late-onset Fragile X-associated tremor/ataxia syndrome attributed to the neurotoxic effect of elevated FMR1 transcripts. Our earlier data suggested that both grey-zone and low-end premutation alleles might also play a sign...

Large cerebral ventricles are a frequent finding in brains of dogs with brachycephalic skull conformation, in comparison with mesaticephalic dogs. It remains unclear whether oversized ventricles represent a normal variant or a pathological condition in brachycephalic dogs. There is a distinct relationship between white matter and grey matter in the cerebrum of all eutherian mammals. The aim of ...

Major advances have been made in the understanding of the neurobiology of psychopathy in the past years, yet the distribution and extent of neuroanatomical abnormalities underlying the disorder are still poorly known. It is also unclear if different dimensions of the construct of psychopathy (e.g., emotional callousness, antisocial behavior) correspond to structural abnormalities in distinct re...

Pure autonomic failure (PAF) is characterized by an acquired, selective, peripheral denervation of the autonomic nervous system. Patients with PAF fail to generate bodily states of arousal via the autonomic nervous system in response to physical or cognitive effort. We used voxel-based morphometry to test the hypothesis that changes in the morphology of brain regions involved in autonomic contr...

BACKGROUND The question of whether Asperger syndrome can be distinguished from autism has attracted much debate and may even incur delay in diagnosis and intervention. Accordingly, there has been a proposal for Asperger syndrome to be subsumed under autism in the forthcoming Diagnostic and Statistical Manual of Mental Disorders, fifth edition, in 2013. One approach to resolve this question has ...